孟加拉国一家三级教学医院下呼吸道感染 (LRTI) 的细菌学概况和抗生素图谱

Talha KA
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引用次数: 0

摘要

简介下呼吸道感染(LRTI)是世界上常见的传染病之一,尤其是在发展中国家。这也给医疗系统造成了巨大的经济负担:这是一项横断面描述性研究,旨在了解 LRTI 患者痰液的感染模式和抗生素图谱。研究地点为锡尔赫特女子医学院附属医院。研究时间为 6 个月。样本量为 684 份:阳性样本占所有样本的 60.4%。男性和女性的比例分别为 61.1%和 38.9%。近一半参与者(49.56%)的年龄在 60 岁或以上。最常见的革兰氏阳性菌是金黄色葡萄球菌(37.87%),最常见的革兰氏阴性菌是Klbsiellaspp(23.39%)。最常见的敏感抗生素是哌拉西林和他唑巴坦(93.86%)、亚胺培南(93.71%)和美罗培南(90.64%):使用适当的抗生素对预防抗生素耐药性至关重要。机构和地区抗生素图谱有助于选择经验性抗生素的决策。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Bacteriological Profile and Antibiogram of Lower Respiratory Tract Infection (LRTI) in a Tertiary Teaching Hospital of Bangladesh
Introduction: Lower respiratory tract infection (LRTI) is one of the common infectious diseases in the world especially in the developing countries. This causes a large financial burden to healthcare system too. Methodology: This was a cross-sectional descriptive study to find out the infection patter and antibiogram of sputum of LRTI patients. Study place was Sylhet Women’s Medical College Hospital. Study period was 6 months. Sample size 684. Results: This positive samples were 60.4% of all the samples. Male and female percentage were 61.1% and 38.9% respectively. The age of the nearly half (49.56%) of the participants were 60 years or above. Commonest isolated Gram-positive bacteria was Staphylococcus aureus (37.87%) and commonest Gram-negative bacteria was Klbsiellaspp (23.39%). Commonest sensitive antibiotics were Piperacillin & Tazobactam (93.86%), Imipenem (93.71%) and Meropenem (90.64%). Conclusion: Use of proper antibiotic is essential to prevent antibiotic resistance. Institutional and regional antibiogram can help in decision making for selecting empirical antibiotic.
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