周期性呕吐综合征:从病理生理学到治疗方法

IF 1.5 Q3 GASTROENTEROLOGY & HEPATOLOGY
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引用次数: 0

摘要

周期性呕吐综合征(CVS)是一种疾病,其特征是反复发作且无法预测的剧烈呕吐,其间夹杂着明显的安宁期。这种疾病主要影响儿童和青少年,但也可能持续到成年,最近医学文献对其进行了广泛的研究和分析。本综述旨在研究 CVS 的流行病学、病理生理学、亚型、诊断标准和当前管理等最重要的方面。尽管确切的病因尚不清楚,但遗传因素(多态性)、神经系统改变和自律神经失调以及环境因素(使用和滥用大麻素)被推测为可能的诱因。CVS 在诊断方面有很大的挑战,因为目前还没有特异性的检测方法来确认它的存在。需要对症状进行彻底评估,并排除导致反复呕吐的其他可能原因。CVS 的治疗通常涉及多学科方法。可选择药物治疗,如止吐药和预防性药物,以及行为和心理支持疗法。根据每位患者的不同需求进行个性化治疗至关重要。尽管人们对 CVS 的认识不断进步,但它仍然是一项重大的临床挑战。这种疾病影响着患者及其家人的生活质量,因此需要不断研究和开发更有效的治疗策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Síndrome de vómitos cíclicos: de la fisiopatología al tratamiento

Cyclic vomiting syndrome (CVS) is a disorder characterized by recurrent and unpredictable episodes of intense vomiting, interspersed with periods of apparent wellbeing. This disorder, which primarily affects children and adolescents but can persist into adulthood, has recently been the subject of extensive study and analysis in the medical literature. The aim of the present review is to examine the most important aspects of the epidemiology, pathophysiology, subtypes, diagnostic criteria, and current management of CVS. Even though the exact etiology remains unknown, genetic factors (polymorphisms), nervous system alterations and autonomic dysregulation, and environmental factors (use and abuse of cannabinoids) are postulated as possible triggers. CVS has significant diagnostic challenges, given that there is no specific test for confirming its presence. Thorough evaluation of symptoms and the ruling out of other possible causes of recurrent vomiting are required. Management of CVS typically involves a multidisciplinary approach. Pharmacologic options are explored, such as antiemetics and preventive medications, as well as behavioral and psychologic support therapies. Treatment personalization is essential, adapting it to the individual needs of each patient. Despite advances in the understanding of CVS, it remains a significant clinical challenge. This disorder impacts the quality of life of those affected and their families, underscoring the ongoing need for research and the development of more effective treatment strategies.

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来源期刊
Revista de Gastroenterologia de Mexico
Revista de Gastroenterologia de Mexico GASTROENTEROLOGY & HEPATOLOGY-
CiteScore
1.60
自引率
12.50%
发文量
102
审稿时长
12 weeks
期刊介绍: La Revista de Gastroenterología de México es el órgano oficial de la Asociación Mexicana de Gastroenterología. Sus espacios están abiertos a los miembros de la Asociación como a todo miembro de la comunidad médica que manifieste interés por utilizar este foro para publicar sus trabajos, cumpliendo con las políticas editoriales que a continuación se mencionan. El objetivo principal de la Revista de Gastroenterología de México, es publicar trabajos originales del amplio campo de la gastroenterología, así como proporcionar información actualizada y relevante para el área de la especialidad y áreas afines. Los trabajos científicos incluyen las áreas de Gastroenterología clínica, endoscópica, quirúrgica y pediátrica.
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