Impact of Vitamin D Supplementation on Glycaemic Control in Type 2 Diabetes Patients: A Double Blind Randomized Controlled Trial

Introduction: Vitamin D deficiency is a global health concern affecting diverse populations and it has been linked to various ailments. This study aimed to investigate vitamin D levels among T2DM patients and evaluate the impact of supplementation on those deficient, alongside its effect on quality of life and comorbidities. Methodology: A double-blinded randomized controlled trial was conducted among T2DM patients aged 18-75 years with HbA1c ≥ 7% and vitamin D deficiency (<12 ng/mL). Participants were divided into intervention (vitamin D supplementation) and control (placebo) groups. Data on demographics, diabetic status, and comorbidities were collected. Blood samples were analyzed for HbA1c and Vitamin D levels. Results: Of the 66 participants initially recruited, 60 completed the study. No adverse effects were observed. There was no significant difference in glycemic control between the intervention and control groups at 3 and 6 months. Quality of life showed no significant improvement with supplementation. Conclusion: This study did not find evidence supporting the efficacy of vitamin D supplementation in improving glycemic control or quality of life among T2DM patients with vitamin D deficiency. Further research is warranted to explore alternative interventions or factors influencing glycemic control and quality of life in T2DM patients.