基于铝酸钙和铝酸锶的新型牙髓胶结物的体外评估

IF 2.7 4区材料科学 Q1 MATERIALS SCIENCE, CERAMICS

Boletin de la Sociedad Espanola de Ceramica y Vidrio Pub Date : 2024-11-01 DOI:10.1016/j.bsecv.2024.06.004

Willams Teles Barbosa , Imarally Vitor de Souza Ribeiro Nascimento , Daniel Bezerra Lima , Francivandi Coelho Barbosa , Benjamin S. Lazarus , Josiane Dantas Viana Barbosa , Marcus Vinicius Lia Fook , Raúl Garcia Carrodeguas , Miguel Ángel Rodriguez

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引用次数: 0

摘要

在根管治疗中，以铝酸盐为基础的根管水门汀具有广阔的前景。铝酸钙具有凝固时间快、可加工性好和生物相容性好等优点，克服了目前可用的三氧化物矿物骨料（MTA）的一些缺点，因此已被用作骨和牙科填充物。同样，铝酸锶也因其作为水门汀的潜力而备受关注。与钙质骨料相比，铝酸锶具有更高的放射性和促进成骨细胞分化的潜力，有利于骨再生。本研究评估了新型牙髓水门汀 CS5C（S3A（三锶铝酸盐（Sr3Al2O6））和 C12A7（十二碳七铝酸钙（Ca12Al14O33））的重量百分比为 80/20）的体外生物特性。体外离子释放测试表明，Al3+、Ca2+ 和 Sr2+ 离子是造成培养基 pH 值偏碱性的原因，从而促进了对所有受测细菌菌株的抗菌活性。它还具有生物相容性，在体外具有良好的细胞粘附性和增殖性。研究结果表明，CS5S 骨水泥在未来作为牙髓骨水泥的应用中具有很大的潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

In vitro evaluation of a new endodontic cement based on calcium and strontium aluminate

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In vitro evaluation of a new endodontic cement based on calcium and strontium aluminate

Aluminate-based endodontic cements are promising in root canal treatments. Calcium aluminates have been used as bone and dental fillers, due to their fast setting time, good workability, and biocompatibility, overcoming some of the disadvantages of mineral trioxide aggregate (MTA) currently available. Similarly, strontium aluminates are of interest, due to their potential as hydraulic cement. They have greater radiopacity than their calcium counterparts and the potential to promote osteoblast differentiation which favors bone regeneration. The present study evaluates the in vitro biological properties of the new endodontic cement CS5C (80/20 wt.% of S₃A (tri-strontium aluminate (Sr₃Al₂O₆)) and C₁₂A₇ (dodeca-calcium hepta-aluminate (Ca₁₂Al₁₄O₃₃))). The in vitro ion release tests showed that Al³⁺, Ca²⁺, and Sr²⁺ ions are responsible for the alkaline pH of the medium, promoting antimicrobial activity against all bacterial strains tested. It also showed biocompatible properties, with promising cellular adhesion and proliferation in vitro. The results revealed that CS5S cement has strong potential for future applications as endodontic cement.

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来源期刊

Boletin de la Sociedad Espanola de Ceramica y Vidrio 工程技术-材料科学：硅酸盐

CiteScore

5.50

自引率

2.90%

发文量

审稿时长

103 days

期刊介绍： The Journal of the Spanish Ceramic and Glass Society publishes scientific articles and communications describing original research and reviews relating to ceramic materials and glasses. The main interests are on novel generic science and technology establishing the relationships between synthesis, processing microstructure and properties of materials. Papers may deal with ceramics and glasses included in any of the conventional categories: structural, functional, traditional, composites and cultural heritage. The main objective of the Journal of the Spanish Ceramic and Glass Society is to sustain a high standard research quality by means of appropriate reviewing procedures.