微波消融治疗肝细胞癌：代谢热对温度分布的影响

Q3 Chemical Engineering

Journal of Advanced Research in Fluid Mechanics and Thermal Sciences Pub Date : 2024-07-04 DOI:10.37934/arfmts.118.2.2433

Heaven Josiah Harvan, Slamet Wahyudi, Winarto

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引用次数: 0

摘要

肝细胞癌是肝癌的主要病因，也是全球发病率最高的癌症之一。微波消融（MWA）是一种通过将肿瘤加热到 50°C 以上来消灭癌细胞的方法。癌组织的新陈代谢热率很高，会影响热疗法的增温和温度分布。这项研究阐明了 MWA 治疗肝癌过程中的代谢热效应。该研究使用彭尼斯生物热传递方程和有限元数值方法，模拟了代谢热值在 368.1 W/m3 到 29000 W/m3 之间的温度分布。代谢热产生的热量低于 MWA 热源。但应考虑温度的升高，因为它会使周围健康组织的温度升高到危险水平。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Microwave Ablation Therapy for Hepatocellular Carcinoma: The Effect of Metabolic Heat on Temperature Distribution

Hepatocellular carcinoma is the main cause of liver cancer and one of the most occurring cancers worldwide. Microwave Ablation (MWA) is a method to destroy cancer cells by heating tumors above 50°C. Cancerous tissues can have high metabolic heat rates and affect temperature gain and distribution in thermal therapies. This research clarifies the metabolic heat effects in MWA therapy of liver cancer. Using Pennes Bioheat transfer equation with finite element numerical method, this research simulates temperature distribution with metabolic heat value ranging from 368,1 W/m3 to 29000 W/m3. The heat generated by metabolic heat is lower than the MWA heat source. However, the temperature increase should be considered as it can increase healthy surrounding tissue temperature to dangerous levels.

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来源期刊

Journal of Advanced Research in Fluid Mechanics and Thermal Sciences Chemical Engineering-Fluid Flow and Transfer Processes

CiteScore

2.40

自引率

0.00%

发文量

176

期刊介绍： This journal welcomes high-quality original contributions on experimental, computational, and physical aspects of fluid mechanics and thermal sciences relevant to engineering or the environment, multiphase and microscale flows, microscale electronic and mechanical systems; medical and biological systems; and thermal and flow control in both the internal and external environment.