基于计算机断层扫描 Hounsfield 单位值的脂肪肝分级与超声波分级

IF 1.5 Q3 GASTROENTEROLOGY & HEPATOLOGY
S. Alshoabi, R. M. Alharbi, Rufaydah Bader Algohani, Shahad Abdullah Alahmadi, Maryam Ahmed, Samah F. Faqeeh, Dalal Alahmadi, A. Qurashi, F. Alhazmi, Rakan Mohammed Alrehaili, Abdulrahman Khalil Almughathawi
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引用次数: 0

摘要

背景:代谢功能障碍相关性脂肪性肝病(MASLD)的范围从肝脂肪变性到非酒精性脂肪性肝炎,并可能导致肝硬化。本研究旨在评估使用非对比计算机断层扫描(NCCT)对 MASLD 进行数字分级的可行性。研究方法在对2020年6月至2024年1月期间诊断为MASLD的166名患者进行的回顾性研究中,通过超声波检查对MASLD进行分级,并通过NCCT测量肝脏密度。对 MASLD 分级和 NCCT 密度进行比较。结果MASLD分级分布如下:0级(79人,占47.6%)、2级(48人,占28.9%)、1级(25人,占15.1%)和3级(14人,占8.4%)。0 级、1 级、2 级和 3 级患者的平均肝脏密度分别为 57.75 HU ± 6.18(范围:48.9-78.2)、51.1 HU ± 4.7(范围:41.4-59.7)、39.3 ± 6.4(范围:21.4-48.9)和 22.87 ± 7.5(范围:12-36.4)。方差分析检验显示,不同分级的 MASLD 患者的平均肝脏密度分布存在显著差异(P < 0.001)。结论超声诊断 MASLD 后,NCCT 为 MASLD 分级提供了一种客观、数值化和可计算的方法,放射科医生、放射技师和感兴趣的医生可以摆脱经验依赖。NCCT 确定,2 级的特异密度为 36.4 至 41.4 HU,与 1 级(41.4-48.9)HU 和 3 级(21.4-36.4 HU)明显重叠。1 级与正常肝脏(48.9-59.7 HU)明显重叠。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Grading of Fatty Liver Based on Computed Tomography Hounsfield Unit Values versus Ultrasonography Grading
Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) ranges from hepatic steatosis to nonalcoholic steatohepatitis and may lead to liver cirrhosis. This study aimed to assess the feasibility of numerical grading MASLD using noncontrast computed tomography (NCCT). Methods: In a retrospective study of 166 patients diagnosed with MASLD between June 2020 and January 2024, MASLD was graded by ultrasonography, and liver density was measured on NCCT. The MASLD grades and NCCT densities were compared. Results: The MASLD grades were distributed as follows: grade 0 (n = 79, 47.6%), grade 2 (n = 48, 28.9%), grade 1 (n = 25, 15.1%), and grade 3 (n = 14, 8.4%). The mean liver density was 57.75 Hounsfield units (HU) ± 6.18 (range: 48.9–78.2), 51.1 HU ± 4.7 (range: 41.4–59.7), 39.3 ± 6.4 (range: 21.4–48.9), and 22.87 ± 7.5 (range: 12–36.4) in the grade 0, grade 1, grade 2, and grade 3 patients, respectively. An analysis of variance test showed significant variance in the distribution of mean liver density in the different MASLD grades (p < 0.001). Conclusions: After ultrasonography diagnosis of MASLD, NCCT offers an objective, numerical, and calculable method for MASLD grading that is available for radiologists, radiologic technologists, and interested physicians away from experience dependence. NCCT determined that grade 2 had a specific density from 36.4 to 41.4 HU that significantly overlapped with grade 1 (41.4–48.9) HU and with grade 3 (21.4–36.4 HU). Grade 1 showed a significant overlap with the normal liver (48.9–59.7 HU).
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来源期刊
Gastroenterology Insights
Gastroenterology Insights GASTROENTEROLOGY & HEPATOLOGY-
CiteScore
2.80
自引率
3.40%
发文量
35
审稿时长
10 weeks
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