阿育吠陀草药矿物质配方 Madhumalini Vasant Ras 片剂的初步理化评估

IF 0.1 Q4 MEDICINE, RESEARCH & EXPERIMENTAL
Shriniwas Jadhav, A. V, Mahesh S
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引用次数: 0

摘要

导言:根据世卫组织的报告,世卫组织 170 个成员国一直在使用各种本土传统药物。为了对阿育吠陀药物进行全球重组,可能需要采用先进的标准化技术来保证质量。Madhumalini Vasant Ras(MVR)是一种著名的阿育吠陀草本矿物质配方,用于治疗子宫内发育迟缓(IUGR)。印度阿育吠陀药方集》中没有提到这种配方,也没有关于 MVR 质量标准的数据。因此,在本研究中,将对 Madhumalini vasant Ras 的理化分析和 HPTLC 评估进行初步数据分析。目的和目标评估 MVR 药片的理化参数并生成相关数据。材料与方法:原料药由 Dravya Guna 和 Rassastra Bhaishajya Kalpana 部门的专家鉴定,并在瓦多达拉的 Parul Ayurveda 学院药房制备片剂(125 毫克)。然后检查了理化参数和微生物限度,并进行了 HPTLC 分析。结果:在评估理化参数时,pH 值为 4.19,LOD 值为 6.01%,总灰分值为 11.54%,酸性不溶性灰分值为 8.70%,水溶性萃取值为 22.20%(重量百分比),醇溶性萃取值为 13.40%(重量百分比),HPTLC 在 254 纳米和 366 纳米波长处显示出五个常见斑点。微生物分析表明,该配方不含微生物。结论关于 MVR 片剂的感官特征、抗菌评价、各种理化参数和 HPTLC 的初步数据已经生成。这些数据可作为今后标准化研究的标准。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Preliminary Physicochemical Evaluation of Madhumalini Vasant Ras tablet – An Ayurveda Herbo-mineral Formulation
Introduction: As per WHO reports, 170 WHO member states have been practicing various indigenous traditional medicines. For the global reorganisation of Ayurvedic drugs advanced standardisation techniques may be involved to maintain quality assurance. Madhumalini Vasant Ras (MVR) is a well-known Ayurvedic herbo-mineral formulation used in the treatment of IUGR (Intra Uterine Growth Retardation). This formulation is not mentioned in the Ayurveda Formulary of India and there is no data on the quality standards of MVR available. So in this study, preliminary data on physicochemical analysis along with HPTLC evaluation of Madhumalini vasant Ras is generated. Aim and objective: To evaluate and generate data on the physicochemical parameters of the MVR tablet. Materials and Method: The raw drugs were authenticated by experts of Dravya Guna and Rassastra Bhaishajya Kalpana departments and tablets (125 mg) were prepared at the pharmacy, Parul institute of Ayurveda, Vadodara. Then the physico-chemical parameters and microbial limits were checked and HPTLC analysis was done. Results: While evaluating the physicochemical parameters, the pH value was 4.19, LOD 6.01%, Total ash value 11.54%, Acid insoluble ash 8.70%, water-soluble extractive value was 22.20% w/w, alcohol soluble extractive value was 13.40% w/w, HPTLC at 254 nm and at 366 nm showed five common spots. The Microbiological analysis shows that the formulation is free from microbes. Conclusion: Preliminary data on organoleptic characters, antimicrobial evaluation, various physicochemical parameters and HPTLC of MVR tablet is generated. These data can be used as a standard for future standardization studies.
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来源期刊
International Journal of Ayurvedic Medicine
International Journal of Ayurvedic Medicine MEDICINE, RESEARCH & EXPERIMENTAL-
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50.00%
发文量
87
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