四个撒哈拉以南非洲国家中早期遭受性暴力的女性艾滋病毒感染者的艾滋病毒感染结果

Chiara-lyse Lee, Andrea Low, Philip Kreniske, O. Mugurungi, F. Ndagije, L. Tenthani, Elaine J. Abrams, C. Teasdale
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摘要

早期的性暴力经历可能会影响女性艾滋病病毒感染者(WLHIV)的艾滋病护理和治疗效果。我们研究了女性艾滋病病毒感染者自述的被迫发生第一次性行为的经历是否与对艾滋病病毒呈阳性状态的认知、接受抗逆转录病毒疗法(ART)和病毒学抑制有关。 我们利用从 2015 年到 2017 年在莱索托、马拉维、赞比亚和津巴布韦开展的具有全国代表性的横断面人群艾滋病影响评估(PHIA)调查进行了二次分析。 采用调查权重和泰勒序列线性化的调整逻辑回归模型来衡量强迫首次性行为与以下三种艾滋病结果之间的关系:(1)所有 WLHIV 对艾滋病病毒感染状况的了解;(2)已知感染状况的 WLHIV 接受抗逆转录病毒疗法的情况;(3)接受抗逆转录病毒疗法的 WLHIV 病毒学抑制情况。 在 WLHIV 中,13.9% 的人报告了被迫的初次性行为。与没有被迫发生第一次性行为的 WLHIV 相比,被迫发生第一次性行为的 WLHIV 知道自己感染艾滋病毒的几率没有差异(调整后的几率比(aOR)为 1.17;95% CI:0.95-1.45)。与没有强迫发生第一次性行为的 WLHIV 相比,强迫发生第一次性行为的 WLHIV 接受抗逆转录病毒疗法的几率明显较低(aOR 0.74,95% CI:0.57-0.96),但病毒学抑制的几率并不低(aOR 1.06,95% CI:0.80-1.42)。 虽然接受抗逆转录病毒疗法的 WLHIV 比例很高,但报告非自愿初次性行为与接受抗逆转录病毒疗法的可能性较低有关,这可能表明早期生活创伤可能会影响长期健康结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
HIV outcomes among women living with HIV who experienced early sexual violence across four sub-Saharan African countries
Early experiences of sexual violence may influence HIV care and treatment outcomes among women living with HIV (WLHIV). We examined whether self-report by WLHIV of being forced into their first sexual experience was associated with awareness of HIV-positive status, being on antiretroviral therapy (ART) and being virologically suppressed. We conducted a secondary analysis using nationally-representative, cross-sectional Population-based HIV Impact Assessment (PHIA) surveys from Lesotho, Malawi, Zambia, and Zimbabwe conducted from 2015 through 2017. Adjusted logistic regression models with survey weights and Taylor series linearization were used to measure the association between forced first sex and three HIV outcomes: (1) knowledge of HIV status among all WLHIV, (2) being on ART among WLHIV with known status, and (3) virologic suppression among WLHIV on ART. Among WLHIV, 13.9% reported forced first sex. Odds of knowledge of HIV status were not different for WLHIV with forced first sex compared to those without (adjusted odds ratio (aOR) 1.17; 95% CI: 0.95-1.45). WLHIV with forced first sex had significantly lower odds of being on ART (aOR 0.74, 95% CI: 0.57-0.96) but did not have lower odds of virological suppression (aOR 1.06, 95% CI: 0.80-1.42) compared to WLHIV without forced first sex. While high proportions of WLHIV were on ART, report of non-consensual first sex was associated with lower likelihood of being on ART which may suggest that early life trauma could influence long term health outcomes.
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