从菲律宾北萨马省老港采集的 Melia azedarach(金莓)叶提取物的生化分析

Jenny Cyrill T. Coria, Flyndon Mark S. Dagalea, M. J. M. Somoray
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摘要

Melia azedarach 属于 Meliaceae 科,有多种名称,如 Chinaberry、Ride of India、Bead-tree、Cape lilac、Persian lilac。它常见于温暖的热带地区,包括东南亚和世界其他许多地方。其叶、树皮、茎和根具有药用价值,对单纯疱疹病毒有效。本研究的重点是分析金樱子叶提取物的生物活性潜力。从颜色、气味、溶解度、沸点、密度和 pH 值等方面测定了其物理性质。 此外,还测定了生物碱、酚类、单宁、皂苷和酚类化合物等次生代谢物。同样,傅立叶变换红外光谱法也用于确定叶提取物中存在的官能团。最后,使用紫外可见(UV-vis)分光光度计来确定金合欢叶提取物的生物活性潜力。 结果表明,金合欢叶呈黄绿色,气味宜人,可与乙醇和水混溶,不与苯混溶,沸点比水低,密度比水小,pH 值呈中度酸性。此外,植物化学筛选结果显示,生物碱、酚类、单宁、皂苷和酚类化合物均呈阳性,这意味着该植物样本可用作抗氧化剂、镇痛剂和消炎药。随后,傅立叶变换红外光谱和紫外-可见光谱分析显示,次生代谢物的官能团和生物活性潜力的测定结果呈阳性,这意味着它可以应用于开发治疗药物和天然疗法。因此,这项研究的结果将造福于整个科学界,因为它将提供更多的信息和证据,为医药开发提供可能的应用。此外,这项研究对整个科学界都有益处,因为它将提供更多关于这些树叶提取物中生物活性潜力特征的信息。同时,它还为常见的健康问题提供了替代疗法,尤其是在那些现代医疗服务有限的偏远地区。总之,这种化合物简化了治疗方法,可能会降低医疗成本,并显著提高生活质量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Biochemical Analysis of Melia azedarach (Chinaberry) Leaf Extract Collected from Laoang, Northern Samar, Philippines
Melia azedarach belongs to the Meliaceae family and is known by various names, such as Chinaberry, ride of India, Bead-tree, Cape lilac, Persian lilac. It is commonly found in warmer and tropical regions, including Southeast Asia and various other parts of the world. The leaves, bark, stem and roots have a medicinal application and effective against the herpes simplex virus. This study focuses on the characterization of bioactive potential of Melia azedarach (Chinaberry) leaf extract. Physical properties were determined in terms of color, odor, solubility, boiling point, density, and pH.  Furthermore, the secondary metabolites were determined in terms of alkaloids, phenols, tannin, saponin, and phenolic compound. Likewise, Fourier-Transform Infrared Spectroscopy is used to determine the functional group present on the leaf extract. Lastly, to determine the bioactive potential of Melia azedarach (Chinaberry) leaf extract Ultraviolet Visible (UV-vis) Spectrophotometer was used.  Result showed that Melia azedarach (Chinaberry) has a yellow green color with a pleasant odor, miscible with ethanol and water, immiscible with benzene, lower boiling point than water, less dense than water and a pH which is moderately acidic. Furthermore, a positive result showed in phytochemical screening for alkaloids, phenols, tannin, saponin and phenolic compound, which implies that the plant sample can be used as antioxidant, analgesic, and anti-inflammatory. Subsequently, FTIR and UV-vis analysis showed a positive result for the determination of functional group and bioactive potential among secondary metabolites which means that it is possible for the application in developing therapeutic medicines and in developing natural remedies. Therefore, the findings of this study will benefits the whole scientific community since it would provide added information and evidences as possible application for the development of pharmaceutical medicine. Furthermore, this study is beneficial to the whole scientific community since it would provide added information about the characterization of bioactive potential present in these leaf extract. It also, provides alternative treatments for common health issues particularly in communities that are in far-flung areas with limited access to modern healthcare. Overall, this compound simplifies treatments, may lower healthcare costs, and significantly improves quality of life.
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