应激性创伤事件、人格特质和精神障碍在慢性疼痛综合征形成过程中的作用

D. Petelin, E. M. Anpilogova, A. O. Tolokonin, Aysylu N. Galiautdinova, O. N. Voskresenskaya, B. Volel
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引用次数: 0

摘要

背景:慢性疼痛综合征是一种发病率很高的疾病,它对工作能力和生活质量产生负面影响,并使疾病的预后恶化,增加早期死亡的风险。最重要的科学和实用医学任务之一是确定从急性疼痛转变为慢性疼痛的风险因素,从而在未来建立预防慢性疼痛发展的机制。已经证实,各种心理和精神病理因素,特别是人格特征和精神障碍、精神创伤事件,对疼痛的持续存在有重要作用,但这些数据需要澄清。目的:确定应激事件、人格特征和合并精神障碍对慢性疼痛综合征形成的贡献。材料与方法:该研究纳入了 105 名年龄在 18 至 70 岁之间、患有不明原因的躯体或神经疼痛综合征、病程超过 6 个月并因此住院治疗的患者。所有患者均接受了临床-心理测试和心理测量检查,并使用 SPSS 统计软件 v22 对结果进行了统计处理。结果:在研究过程中,对合并有慢性疼痛的精神障碍患者进行了分组,共分为四组:1 - 长期应激反应/疲惫障碍框架内的慢性疼痛,42 名观察对象(12 名男性,30 名女性);2 - 长期掩饰性抑郁发作框架内的慢性疼痛,41 名观察对象(6 名男性,35 名女性);3 - 作为疑病症谱系障碍(局限性疑病症)一部分的慢性疼痛,15 例(男性 8 例,女性 7 例); 4 - 作为具有疼痛倾向的体质异常(疼痛易感人格)一部分的慢性疼痛,7 例(男性 5 例,女性 2 例)。结论:慢性疼痛综合征与应激事件有明显的关联。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The role of stressful traumatic events, personality traits and psychiatric disorders in the formation of chronic pain syndromes
BACKGROUND: Chronic pain syndrome is a highly prevalent condition that negatively affects the ability to work and quality of life, as well as worsening the prognosis of the disease and increasing the risk of early death. One of the most important scientific and practical medical tasks is the identification of risk factors for the transition of acute pain to chronic pain, which in the future will allow to develop mechanisms for preventing the development of chronic pain. It has been established that various psychological and psychopathological factors, in particular, personality traits and mental disorders, psychotraumatic events, make a significant contribution to the perpetuation of pain, but these data require clarification. AIM: To determine the contribution of stressful events, personality profile and comorbid psychiatric disorders to the formation of chronic pain syndromes. MATERIALS AND METHODS: The study included 105 patients aged 18 to 70 years with unexplained somatic or neurological pain syndrome that existed for more than 6 months and served as a reason for hospitalization. All patients underwent clinical-anamnestic and psychometric examination, statistical processing of the results was performed using SPSS Statistics v22. RESULTS: In the course of the study, 4 groups of patients with psychiatric disorders comorbid with chronic pain were formed: 1 — chronic pain within the framework of prolonged reaction to stress\exhaustion disorder, 42 observations (12 men, 30 women); 2 — chronic pain within the framework of prolonged masked depressive episodes, 41 observations (6 men, 35 women); 3 — chronic pain as part of hypochondriacal spectrum disorders (limited hypochondria), 15 observations (8 men, 7 women); 4 — chronic pain as part of constitutional anomalies with a tendency to experience pain (pain prone personality), 7 observations (5 men, 2 women). CONCLUSION: A significant association of chronic pain syndromes with stressful events has been established.
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