Ramazan Er Erdem, Mehmet Bektaş, Zeynep M Ellik, Koray Ceyhan
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Giovannini's classification was performed according to the elastography images recorded in the system. The effectiveness of SR and Gc in the distinction between GIST and leiomyomas was evaluated.</p><p><strong>Results: </strong>Twelve of the GISTs and 3 of the leiomyomas were with scores 4 and 5 according to Gc (<i>p</i> = 0.006). Gastrointestinal stromal tumors had a higher SR than leiomyomas (<i>p</i> = 0.001). For the diagnosis of GISTs, sensitivity/specificity/diagnostic accuracy were 92.3%/80%/87% for SR alone, 92.3%/70%/82.6% for Gc alone, and 84.6%/80%/82.6% for the use of both SR and Gc.</p><p><strong>Conclusions: </strong>This is the first study in which semi-quantitative (SR) and qualitative (Gc) methods were evaluated together for the distinction of GISTs and leiomyomas. The sensitivity of SR alone for diagnosing GIST is higher than that of Gc alone or the combination of both methods. Although SR alone does not diagnose GIST, it can be used as an auxiliary method in biopsy and follow-up decisions.</p><p><strong>How to cite this article: </strong>Erdem RE, Bektaş M, Ellik ZM, <i>et al.</i> Use of Endoscopic Ultrasound Elastography to Differentiate between Gastrointestinal Stromal Tumor and Leiomyoma Localized in the Upper Gastrointestinal Tract. Euroasian J Hepato-Gastroenterol 2024;14(1):20-23.</p>","PeriodicalId":516317,"journal":{"name":"Euroasian journal of hepato-gastroenterology","volume":"14 1","pages":"20-23"},"PeriodicalIF":0.0000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11249890/pdf/","citationCount":"0","resultStr":"{\"title\":\"Use of Endoscopic Ultrasound Elastography to Differentiate between Gastrointestinal Stromal Tumor and Leiomyoma Localized in the Upper Gastrointestinal Tract.\",\"authors\":\"Ramazan Er Erdem, Mehmet Bektaş, Zeynep M Ellik, Koray Ceyhan\",\"doi\":\"10.5005/jp-journals-10018-1419\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Gastrointestinal stromal tumors (GISTs) have malignant potential. Distinction of GISTs from leiomyoma is important to the decision of follow-up or treatment for upper gastrointestinal tract subepithelial lesions (SELs). There are few studies on the evaluation of gastrointestinal SELs with endoscopic ultrasound (EUS) elastography.</p><p><strong>Aims: </strong>To evaluate the efficiency of strain ratio (SR) measurement and Giovannini's classification (Gc) by EUS elastography in differentiating GISTs from leiomyomas.</p><p><strong>Materials and methods: </strong>Twenty-three lesions with histopathological diagnoses of 13 GISTs and 10 leiomyomas were evaluated. The lesions' SR values were obtained from EUS reports retrospectively. Giovannini's classification was performed according to the elastography images recorded in the system. The effectiveness of SR and Gc in the distinction between GIST and leiomyomas was evaluated.</p><p><strong>Results: </strong>Twelve of the GISTs and 3 of the leiomyomas were with scores 4 and 5 according to Gc (<i>p</i> = 0.006). Gastrointestinal stromal tumors had a higher SR than leiomyomas (<i>p</i> = 0.001). For the diagnosis of GISTs, sensitivity/specificity/diagnostic accuracy were 92.3%/80%/87% for SR alone, 92.3%/70%/82.6% for Gc alone, and 84.6%/80%/82.6% for the use of both SR and Gc.</p><p><strong>Conclusions: </strong>This is the first study in which semi-quantitative (SR) and qualitative (Gc) methods were evaluated together for the distinction of GISTs and leiomyomas. The sensitivity of SR alone for diagnosing GIST is higher than that of Gc alone or the combination of both methods. Although SR alone does not diagnose GIST, it can be used as an auxiliary method in biopsy and follow-up decisions.</p><p><strong>How to cite this article: </strong>Erdem RE, Bektaş M, Ellik ZM, <i>et al.</i> Use of Endoscopic Ultrasound Elastography to Differentiate between Gastrointestinal Stromal Tumor and Leiomyoma Localized in the Upper Gastrointestinal Tract. 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引用次数: 0
摘要
背景：胃肠道间质瘤（GIST）具有恶性潜能。区分胃肠道间质瘤和子宫肌瘤对决定上消化道上皮下病变（SELs）的随访或治疗非常重要。目的：评估通过 EUS 弹性成像测量应变比（SR）和 Giovannini 分类（Gc）区分胃肠道上皮下病变和子宫肌瘤的效率：评估了 23 个病灶，组织病理学诊断为 13 个 GIST 和 10 个子宫肌瘤。病变的 SR 值来自 EUS 的回顾性报告。根据系统记录的弹性成像图像进行了乔瓦尼尼分类。评估了 SR 和 Gc 在区分 GIST 和子宫肌瘤方面的有效性：结果：12 例胃肠道间质瘤和 3 例子宫肌瘤的 Gc 评分分别为 4 分和 5 分（p = 0.006）。胃肠道间质瘤的 SR 值高于子宫肌瘤（p = 0.001）。对于胃肠道间质瘤的诊断，单独使用SR的敏感性/特异性/诊断准确性分别为92.3%/80%/87%，单独使用Gc的敏感性/特异性/诊断准确性分别为92.3%/70%/82.6%，同时使用SR和Gc的敏感性/特异性/诊断准确性分别为84.6%/80%/82.6%：这是第一项同时评估半定量（SR）和定性（Gc）方法以区分胃肠道间质瘤和子宫肌瘤的研究。单独使用 SR 诊断 GIST 的灵敏度高于单独使用 Gc 或两种方法的组合。虽然SR不能单独诊断GIST，但可作为活检和随访决策的辅助方法：Erdem RE, Bektaş M, Ellik ZM, et al.Euroasian J Hepato-Gastroenterol 2024;14(1):20-23.
Use of Endoscopic Ultrasound Elastography to Differentiate between Gastrointestinal Stromal Tumor and Leiomyoma Localized in the Upper Gastrointestinal Tract.
Background: Gastrointestinal stromal tumors (GISTs) have malignant potential. Distinction of GISTs from leiomyoma is important to the decision of follow-up or treatment for upper gastrointestinal tract subepithelial lesions (SELs). There are few studies on the evaluation of gastrointestinal SELs with endoscopic ultrasound (EUS) elastography.
Aims: To evaluate the efficiency of strain ratio (SR) measurement and Giovannini's classification (Gc) by EUS elastography in differentiating GISTs from leiomyomas.
Materials and methods: Twenty-three lesions with histopathological diagnoses of 13 GISTs and 10 leiomyomas were evaluated. The lesions' SR values were obtained from EUS reports retrospectively. Giovannini's classification was performed according to the elastography images recorded in the system. The effectiveness of SR and Gc in the distinction between GIST and leiomyomas was evaluated.
Results: Twelve of the GISTs and 3 of the leiomyomas were with scores 4 and 5 according to Gc (p = 0.006). Gastrointestinal stromal tumors had a higher SR than leiomyomas (p = 0.001). For the diagnosis of GISTs, sensitivity/specificity/diagnostic accuracy were 92.3%/80%/87% for SR alone, 92.3%/70%/82.6% for Gc alone, and 84.6%/80%/82.6% for the use of both SR and Gc.
Conclusions: This is the first study in which semi-quantitative (SR) and qualitative (Gc) methods were evaluated together for the distinction of GISTs and leiomyomas. The sensitivity of SR alone for diagnosing GIST is higher than that of Gc alone or the combination of both methods. Although SR alone does not diagnose GIST, it can be used as an auxiliary method in biopsy and follow-up decisions.
How to cite this article: Erdem RE, Bektaş M, Ellik ZM, et al. Use of Endoscopic Ultrasound Elastography to Differentiate between Gastrointestinal Stromal Tumor and Leiomyoma Localized in the Upper Gastrointestinal Tract. Euroasian J Hepato-Gastroenterol 2024;14(1):20-23.
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