Juan Salazar, Mayela Bracho, Carlos Esis, Roberto Añez-Ramos
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引用次数: 0
摘要
心脏淀粉样变性(CA)是一种浸润性疾病,其特点是错误折叠的蛋白质沉积在心脏间质组织中。在过去的十年中,人们对这种病理现象的研究兴趣与日俱增,因为新的流行病学研究表明,这种疾病并不像以前认为的那样罕见。同样,非侵入性诊断方法的进步以及对改变其长期发展(甚至是死亡率)的分子的鉴定,也增强了人们对 CA 的兴趣。尽管如此,在委内瑞拉,CA 的诊断仍然存在局限性,部分原因与对该疾病缺乏了解有关。因此,临床心脏病专家有必要进一步努力提高对该疾病的诊断技能,因为及时发现该疾病是有效治疗的关键一步。
Cardiac Amyloidosis in Venezuela: A Pending Issue.
Cardiac amyloidosis (CA) is an infiltrative disease characterized by the deposition of misfolded proteins in cardiac interstitial tissue. Interest towards studying this pathology has been growing in the last decade, as new epidemiological insights have revealed that it is not as uncommon as previously believed. Likewise, advances in non-invasive diagnostic approaches and the identification of molecules that modify its long-term progression, even in terms of mortality, have also bolstered interest in CA. Despite this global panorama, in Venezuela, limitations remain regarding the diagnosis of CA, partly associated with a lack of knowledge of the disease. Therefore, additional efforts are necessary for clinical cardiologists to hone their diagnostic skills regarding this disease, as opportune identification is an essential step for its effective management.
期刊介绍:
Current Cardiology Reviews publishes frontier reviews of high quality on all the latest advances on the practical and clinical approach to the diagnosis and treatment of cardiovascular disease. All relevant areas are covered by the journal including arrhythmia, congestive heart failure, cardiomyopathy, congenital heart disease, drugs, methodology, pacing, and preventive cardiology. The journal is essential reading for all researchers and clinicians in cardiology.