功能性额叶切除术在药物耐药性额叶癫痫外科治疗中的应用：我是怎么做的。

IF 1.9 3区医学 Q3 CLINICAL NEUROLOGY

Acta Neurochirurgica Pub Date : 2024-07-18 DOI:10.1007/s00701-024-06176-x

Francesca Battista, Alice Esposito, Giovanni Muscas, Alessandro Della Puppa

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引用次数: 0

摘要

背景：30%的额叶癫痫具有药物抵抗性，占癫痫手术的10%-20%。对于无病灶癫痫（磁共振成像阴性）病例，额叶切除术是一种重要的治疗方法，历史上额叶解剖切除术（AFL）的并发症风险为33.3%，癫痫发作控制率为55.7%：方法：我们介绍了额叶功能切除术（FFL），该术式根据患者的皮质-皮质下功能区确定边界，并通过先进的术中技术，如束成像和导航经颅磁刺激（nTMS）进行识别：结论：与 AFL 相比，FFL 允许更广泛的切除，术后并发症发生率更低。

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Functional frontal lobectomy in the surgical treatment of pharmacoresistant frontal lobe epilepsy: how I do it.

Background: Frontal lobe epilepsy is pharmacoresistant in 30% of cases, constituting 10-20% of epilepsy surgeries. For cases of no lesional epilepsy (negative MRI), frontal lobectomy is a crucial treatment, historically involving Frontal Anatomical Lobectomy (AFL) with a 33.3% complication risk and 55.7% seizure control.

Methods: We describe Frontal Functional Lobectomy (FFL), in which the boundaries are defined on the patient's functional cortico-subcortical areas, recognized with advanced intraoperative technologies such as tractography and navigated transcranial magnetic stimulation (nTMS).

Conclusions: The FFL allows for a broader resection with a lower rate of postoperative complications than the AFL.

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来源期刊

Acta Neurochirurgica 医学-临床神经学

CiteScore

4.40

自引率

4.20%

发文量

342

审稿时长

1 months

期刊介绍： The journal "Acta Neurochirurgica" publishes only original papers useful both to research and clinical work. Papers should deal with clinical neurosurgery - diagnosis and diagnostic techniques, operative surgery and results, postoperative treatment - or with research work in neuroscience if the underlying questions or the results are of neurosurgical interest. Reports on congresses are given in brief accounts. As official organ of the European Association of Neurosurgical Societies the journal publishes all announcements of the E.A.N.S. and reports on the activities of its member societies. Only contributions written in English will be accepted.