心脏手术后患者因地高辛-利尿剂相互作用导致的双向室性心动过速:病例报告。

José Martín Alanís-Naranjo, Kevin David Aragón-Ontiveros, Julio César Rivera-Hermosillo, Virginia Campos-Garcilazo
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引用次数: 0

摘要

双向室性心动过速(BVT)是一种罕见的恶性室性心律失常,其特点是 QRS 轴的搏动交替。双向室性心动过速是洋地黄中毒的特征之一,但心脏手术患者因地高辛-利尿剂相互作用而继发地高辛诱导的双向室性心动过速却鲜有报道。我们报告了一例接受二尖瓣置换术和三尖瓣瓣环成形术的 62 岁女性患者,她术后出现充血性心力衰竭和血管痉挛综合征,需要使用去甲肾上腺素、血管加压素和襻利尿剂。在术后护理期间,她出现了心房颤动,心室反应迅速,使用地高辛控制了心率,但后来出现了血流动力学稳定的 BVT,与洋地黄毒性有关。该病例强调了医生在为使用利尿剂(尤其是襻利尿剂)的患者处方地高辛时监测地高辛毒性的重要性。在地高辛诱发的BVT期间,只要没有地高辛特异性抗体,且患者血流动力学稳定,就可以考虑支持性治疗,包括停用洋地黄,同时补充钾和镁。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Bidirectional ventricular tachycardia due to digoxin-diuretic interaction in post-cardiac surgery patient: a case report.

Bidirectional ventricular tachycardia (BVT) is a rare form of malignant ventricular arrhythmia characterized by beat-to-beat alternation in the QRS axis. BVT is a hallmark of digitalis toxicity, but digoxin-induced BVT secondary to digoxin-diuretic interaction in cardiac surgery patients is not widely reported. We present the case of a 62-year-old woman undergoing mitral valve replacement with tricuspid annuloplasty who developed postoperative congestive heart failure and vasoplegic syndrome requiring norepinephrine, vasopressin, and loop diuretics. During postoperative care, she presented atrial fibrillation with rapid ventricular response, achieving rate control with digoxin, but later displayed hemodynamically stable BVT associated with digitalis toxicity. The case highlights the importance of physicians monitoring digoxin toxicity when prescribing digoxin to patients with a diuretic regimen, particularly loop diuretics. During digoxin-induced-BVT, supportive treatment, including discontinuing digitalis coupled with potassium and magnesium supplements, can be considered as long as digoxin-specific antibodies are unavailable, and the patient is hemodynamically stable.

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