使用非交联聚乙烯的第三代双活动度全髋关节置换术在 60 岁以下患者中的效果:8.6 年后全压入式与三脚架杯的比较研究。

IF 2.3 3区 医学 Q2 ORTHOPEDICS
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引用次数: 0

摘要

背景:全髋关节置换术(THA)的双活动度概念是预防脱位和治疗不稳定的一场革命。在 60 岁以下的患者中使用这种方法仍存在争议,因为第一代氧化铝涂层髋臼杯的效果较差。本研究使用多孔双层涂层的现代双活动度(DM)髋臼杯,以60岁以下的活跃患者为对象,旨在评估:(1) 两种最新一代DM THA的机械存活率,失败定义为因机械性松动而对髋臼或股骨假体进行翻修,通过比较三脚架髋臼杯和全压合式髋臼杯;(2) 评估并发症;(3) 比较两种假体的放射学假体周围骨溶解率:假设:无论使用哪种髋臼固定方式,为年轻患者植入的现代DM髋臼杯的中期存活率是相同的:这是一项回顾性研究,研究对象是2005年至2016年期间在111名患者的初次关节置换术中使用的119个最新一代DM THA,采用标准聚乙烯材料,包括66个全压合髋臼杯和53个三脚架固定髋臼杯。存活率研究使用医疗记录进行。临床评估采用改良哈里斯髋关节评分(mHHS)以及自制的髋关节和骨关节炎结果评分(HOOS)和牛津-12问卷。对X光片进行放射学分析,检查骨质脱钙情况以及髋臼和股骨线:在8.6年(5-16年)的时间里,无论使用哪种髋臼杯,都没有发现因机械性松动而进行的翻修。假体脱位率(大关节)为1.7%:每组各有1例(P = 1),其中全压入组有1例需要翻修。有三次因机械并发症而进行翻修的记录:使用前倾角不足的全压合式假体杯时髋关节再次脱位,使用全压合式假体杯时髋臼周围假体骨折,以及使用后倾角的三脚架假体杯时髂腰肌撞击。全因翻修的存活率为:压合型 93.8%(95% CI:88.2%-99.9%),三脚架 96.2%(95% CI:91.1%-100%)(P = 0.63);除感染外,任何原因导致的翻修存活率为:压合型 96.9%(95% CI:92.8%-100%),三脚架 98.1%(95% CI:94.4%-100%)(P = 0.7)。髋臼周围骨溶解率为11%,三脚架髋臼杯(24%,9例)明显高于全压合式髋臼杯(2%,1例)(p < 0.01):该系列研究表明,无论采用哪种髋臼固定方式,带有多孔双层涂层的第三代DM髋臼杯在8.6年的随访中对60岁以下的患者均有良好的疗效。与三脚架髋臼杯不同,全压合式髋臼杯周围的骨溶解率仍然很低。年轻患者可以使用双活动度假体治疗原发性髋关节骨性关节炎,最好使用全压合杯(即不使用任何可能会促进聚乙烯碎片扩散和骨溶解的钉子或额外螺钉):证据等级:III;比较性回顾研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Results of third generation dual mobility total hip arthroplasties with non-cross-linked polyethylene in patients under 60 years of age: comparative study of full pressfit vs. tripod cups after 8.6 years

Background

The concept of dual mobility of total hip arthroplasties (THA) is a revolution in the prevention of dislocations and in the treatment of instability. Its use remains controversial in patients under 60 years old, providing poorer results with first generation cups coated with alumina. This study, carried out on modern dual mobility (DM) cups with a porous bilayer coating, in active patients under 60 years of age aimed to evaluate: (1) the mechanical survival of two latest generation DM THA, with failure defined as revision of acetabular or femoral implants for mechanical loosening, by comparing a tripod cup to a full pressfit cup, (2) to evaluate the complications, (3) to compare the rate of radiographic peri-prosthetic osteolysis between the 2 implants.

Hypothesis

The hypothesis was that the medium-term survival of modern DM cups placed in young patients was the same regardless of the type of acetabular fixation used.

Materials and methods

This was a retrospective study of 119 latest generation DM THA with standard polyethylene, composed of 66 full pressfit cups and 53 tripod fixation cups, used in primary arthroplasty in 111 patients between 2005 and 2016. The survival study was carried out using medical records. The clinical evaluation was carried out using the modified Harris Hip Score (mHHS) as well as the self-administered Hip and Osteoarthritis Outcome Score (HOOS) and Oxford-12 questionnaires. Radiological analysis was carried out on radiographs looking for bone demineralization and acetabular and femoral lines.

Results

At 8.6 years (5–16), no revision for mechanical loosening was observed regardless of the type of cup. The prosthesis dislocation rate (large joint) was 1.7%: 1 case in each group (p = 1), including one revision required in the full pressfit group. Three revisions for mechanical complications were recorded: a recurrent dislocating hip on a full pressfit cup that was not sufficiently anteverted, an acetabular peri-prosthetic fracture on a full pressfit cup and a case of iliopsoas impingement with a retroverted tripod cup. The survival rate for all-cause revision was 93.8% for pressfit (95% CI: 88.2%–99.9%) vs. 96.2% for tripod (95% CI: 91.1%–100%) (p = 0.63) and for revision due to any cause excluding infection, 96.9% for pressfit (95% CI: 92.8%–100%) vs. 98.1% for tripod (95% CI: 94.4%–100%) (p = 0.7). The rate of periacetabular osteolysis was 11%, significantly more present amongst tripod cups (24%, 9 cases) compared to full pressfit cups (2%, 1 case) (p < 0.01).

Conclusion

This series demonstrates good performance of 3rd generation DM cups with porous bilayer coating in patients under 60 years of age regardless of the type of acetabular fixation, at 8.6 years of follow-up. The rate of osteolysis around full pressfit cups remains very low, unlike that of tripod cups. The use of Double Mobility prostheses for primary hip osteoarthritis is possible in young patients, preferably with full pressfit cups (i.e., without any pegs or additional screws that may promote diffusion of polyethylene debris and osteolysis).

Level of evidence

III; comparative retrospective study.

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来源期刊
CiteScore
5.10
自引率
26.10%
发文量
329
审稿时长
12.5 weeks
期刊介绍: Orthopaedics & Traumatology: Surgery & Research (OTSR) publishes original scientific work in English related to all domains of orthopaedics. Original articles, Reviews, Technical notes and Concise follow-up of a former OTSR study are published in English in electronic form only and indexed in the main international databases.
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