[威尼托水污染地区居民膳食全氟和多氟烷基物质摄入量的风险评估。基于 EFSA 2020 限值的更新。2016-2017年食品监测活动]。

IF 1.2 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Annibale Biggeri
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引用次数: 0

摘要

威尼托大区(意大利北部)于 2016-2017 年开展了一项监测活动,以评估 2013 年发现的水污染影响地区食品中的全氟和多氟烷基物质 (PFAS) 的浓度。意大利国家卫生研究院(ISS)于 2018 年对常住人口进行了风险评估,并于 2021 年进行了更新。欧洲食品安全局(EFSA)更新了意大利国家卫生研究所使用的限值,特别是在 2020 年增加了四种 PFAS 分子总和的限值。在本研究中,根据全氟辛酸(PFOA)、全氟辛烷磺酸(PFOS)、全氟壬酸(PFNA)和全氟己烷磺酸(PFHxS)之和每公斤体重 4.4 纳克的新限量,对 ISS 进行的风险评估进行了回顾。在成年人(18-65 岁)中,2013 年之前几年的每周总摄入量是 EFSA 2020 年限值的 10 倍以上,2013-2017 年中间时期(在通过对输水管水进行双重过滤实施减缓行动之前)是其 5 倍以上,2018 年之后是其 3 倍以上,而通过私人水井供应受污染地下水的人群的摄入量几乎是其 7 倍。使用经过滤的自来水管水的居民的食品支出相当于每周总收入的 20%。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Risk appraisal of dietary intake of per- and polyfluoroalkyl substances by the Veneto population living in the area with water contamination. Update based on EFSA 2020 limits. Food surveillance campaign 2016-2017].

The Veneto Region (Northern Italy) conducted a monitoring campaign in the years 2016-2017 in order to evaluate the concentration of per- and polyfluoroalkyl substances (PFASs) in foods in the area affected by the water contamination discovered in 2013. The risk assessment for the resident population was conducted by the Italian National Institute of Health (ISS) in 2018 and updated in 2021. The European Food Safety Agency (EFSA) updated the limits used by ISS, in particular adding a limit for the sum of four PFAS molecules in 2020. In this work, the risk assessment conducted by ISS is reviewed in light of the new limit of 4.4 ng/kg body weight for the sum of perfluorooctanoic acid (PFOA), perfluorooctanesulfonic acid (PFOS), perfluorononanoic acid (PFNA), and perfluorohexanesulfonate (PFHxS). In the adult population (18-65 years), total weekly intakes, calculated for the years preceding 2013, resulted more than ten times the EFSA 2020 limit, more than five times in the intermediate period 2013-2017 - preceding the implementation of mitigation actions through double filtration of the water of the aqueduct -, by more than three times in the period after 2018, and yet by almost seven times for those who supply contaminated groundwater through private wells. The food contribution for those who use filtered water from the aqueduct is equal to 20% of the total weekly income.

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来源期刊
Epidemiologia & Prevenzione
Epidemiologia & Prevenzione 医学-公共卫生、环境卫生与职业卫生
CiteScore
2.60
自引率
14.30%
发文量
0
审稿时长
>12 weeks
期刊介绍: Epidemiologia & Prevenzione, oggi organo della Associazione italiana di epidemiologia, raccoglie buona parte delle migliori e originali esperienze italiane di ricerca epidemiologica e di studio degli interventi per la prevenzione e la sanità pubblica. La rivista – indicizzata su Medline e dotata di Impact Factor – è un canale importante anche per la segnalazione al pubblico internazionale di contributi che altrimenti circolerebbero soltanto in Italia. E&P in questi decenni ha svolto una funzione di riferimento per la sanità pubblica ma anche per i cittadini e le loro diverse forme di aggregazione. Il principio che l’ha ispirata era, e rimane, che l’epidemiologia ha senso se è funzionale alla prevenzione e alla sanità pubblica e che la prevenzione ha ben poche possibilità di realizzarsi se non si fonda su valide basi scientifiche e se non c’è la partecipazione di tutti i soggetti interessati. Modalità di comunicazione aggiornate, metodologia statistica ed epidemiologica rigorosa, validità degli studi e solidità delle interpretazioni dei risultati sono la solida matrice su cui E&P è costruita. A questa si accompagna una forte responsabilità etica verso la salute pubblica, che oggi ha ampliato in forma irreversibile il suo orizzonte, e include in forma sempre più consapevole non solo gli esseri umani, ma l’intero pianeta e le modificazioni che l’uomo apporta all’universo in cui vive. L’ambizione è che l’offerta di nuovi strumenti di comunicazione, informazione e formazione, soprattutto attraverso l''uso di internet, renda la rivista non solo un tradizionale veicolo di contenuti e analisi scientifiche, ma anche un potente strumento a disposizione di una comunità di interessi e di valori che ha a cuore la salute pubblica.
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