利用蒙特卡罗模拟从肺部计算机断层扫描中的剂量-长度乘积估算特定患者的有效剂量

IF 1.1 Q4 ENGINEERING, BIOMEDICAL
Journal of Medical Signals & Sensors Pub Date : 2024-04-18 eCollection Date: 2024-01-01 DOI:10.4103/jmss.jmss_53_22
Gholamreza Fallahmohammadi, Zeinab Kordzini Nodeh, Mohammad Mahdavi
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引用次数: 0

摘要

背景:计算机断层扫描(CT)成像在放射治疗过程中对患者造成的剂量中占很大比重,因此,准确计算这种模式的辐射风险估计是不可避免的。本研究采用蒙特卡罗(MC)模拟法,利用剂量-长度乘积(DLP)指数确定肺部 CT 扫描中患者的特定有效剂量:方法:使用 EGSnrc/BEAMnrc MC 代码模拟 CT 扫描仪。方法:使用 EGSnrc/BEAMnrc MC 代码模拟 CT 扫描仪,使用 DOSxyznrc 模拟代码模拟患者肺部的特定体素化模型,并根据常规肺部 CT 扫描的 X 射线参数对其进行照射,计算输送到胸部器官的剂量。根据两组男性和女性的三种不同体型习惯(苗条、标准和肥胖患者)模拟了三种类型的模型。使用一个系数将 MC 代码中每个粒子的相对剂量转换为绝对剂量。计算了所有肺部器官的剂量,并计算了所有三组患者身体习惯的有效剂量。DLP 指数和容积 CT 剂量指数(CTDIvol)是从患者在 CT 扫描仪上的剂量报告中提取的。计算了不同体型患者的 DLP 与有效剂量的换算系数(k 系数):结果:瘦削、标准和肥胖男性患者的肺辐射剂量分别为 0.164、0.103 和 0.078 mGy/mAs,女性患者的肺辐射剂量分别为 0.164、0.105 和 0.079 mGy/mAs。瘦削患者组(尤其是女性)的 k 因子高于其他组别:结论:有研究报告称,瘦削患者的 CT 扫描剂量指数被低估了。结论:有研究报告称,瘦削患者的 CT 扫描剂量指数被低估了。CT 扫描系统的剂量报告应根据患者的体型按比例进行修改,以准确估计辐射风险。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Patient-specific Effective Dose Estimation from Dose-Length Product in Lung Computed Tomography Using Monte Carlo Simulation.

Patient-specific Effective Dose Estimation from Dose-Length Product in Lung Computed Tomography Using Monte Carlo Simulation.

Patient-specific Effective Dose Estimation from Dose-Length Product in Lung Computed Tomography Using Monte Carlo Simulation.

Background: Computed tomography (CT) imaging has a large portion in the dose of patients from radiological procedures; therefore, accurate calculation of radiation risk estimation in this modality is inevitable. In this study, a method for determining the patient-specific effective dose using the dose-length product (DLP) index in lung CT scan using Monte Carlo (MC) simulation is introduced.

Methods: EGSnrc/BEAMnrc MC code was used to simulate a CT scanner. The DOSxyznrc simulation code was used to simulate a specific voxelized phantom from the patient's lungs and irradiate it according to X-ray parameter of routing lung CT scan, and dose delivered to thorax organs was calculated. Three types of phantoms were simulated according to three different body habits (slim, standard, and fat patients) in two groups of men and women. A factor was used to convert the relative dose per particle in MC code to the absolute dose. The dose was calculated in all lung organs, and the effective dose was calculated for all three groups of patient body habits. DLP index and volume CT dose index (CTDIvol) were extracted from the patient's dose report in the CT scanner. The DLP to effective dose conversion factor (k-factor) for patients with different body habitus was calculated.

Results: Lung radiation dose in slim, standard, and fat patients in men was 0.164, 0.103, and 0.078 mGy/mAs and in women was 0.164, 0.105, and 0.079 mGy/mAs, respectively. The k-factor in the group of slim patients, especially in women, was higher than in other groups.

Conclusions: CT scan dose indexes for slim patients are reported to be underestimated in studies. The dose report in CT scan systems should be modified in proportion to the patient's body habitus, to accurately estimate the radiation risk.

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来源期刊
Journal of Medical Signals & Sensors
Journal of Medical Signals & Sensors ENGINEERING, BIOMEDICAL-
CiteScore
2.30
自引率
0.00%
发文量
53
审稿时长
33 weeks
期刊介绍: JMSS is an interdisciplinary journal that incorporates all aspects of the biomedical engineering including bioelectrics, bioinformatics, medical physics, health technology assessment, etc. Subject areas covered by the journal include: - Bioelectric: Bioinstruments Biosensors Modeling Biomedical signal processing Medical image analysis and processing Medical imaging devices Control of biological systems Neuromuscular systems Cognitive sciences Telemedicine Robotic Medical ultrasonography Bioelectromagnetics Electrophysiology Cell tracking - Bioinformatics and medical informatics: Analysis of biological data Data mining Stochastic modeling Computational genomics Artificial intelligence & fuzzy Applications Medical softwares Bioalgorithms Electronic health - Biophysics and medical physics: Computed tomography Radiation therapy Laser therapy - Education in biomedical engineering - Health technology assessment - Standard in biomedical engineering.
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