{"title":"一例艾滋病毒阳性女性多诺万病病例报告。","authors":"Niharika Kumari, Aanchal Agarwal, Atul Mohan, Satyendra Kumar Singh","doi":"10.4103/ijstd.ijstd_62_23","DOIUrl":null,"url":null,"abstract":"<p><p>Donovanosis is a chronic granulomatous ulcerative sexually transmitted infection caused by Klebsiella (Calymmatobacterium) granulomatis. A 39-year-old female patient with underlying HIV infection presented to the department of dermatology outpatient department with a painless ulcer over the left labia majora for 3 months. Histopathological examination revealed histiocyte which contains granular material resembling coccobacilli and Giemsa staining was positive for Donovan bodies. She was treated with doxycycline 100 mg twice daily and azithromycin 1 g once weekly for 3 weeks and further azithromycin 1 g weekly for the next 9 weeks till complete healing of the lesion. Due to the rarity of this condition in our region, we present this case of donovanosis in an HIV-positive female patient.</p>","PeriodicalId":44880,"journal":{"name":"Indian Journal of Sexually Transmitted Diseases and AIDS","volume":null,"pages":null},"PeriodicalIF":0.6000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11233046/pdf/","citationCount":"0","resultStr":"{\"title\":\"A case report of donovanosis in HIV-positive female.\",\"authors\":\"Niharika Kumari, Aanchal Agarwal, Atul Mohan, Satyendra Kumar Singh\",\"doi\":\"10.4103/ijstd.ijstd_62_23\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Donovanosis is a chronic granulomatous ulcerative sexually transmitted infection caused by Klebsiella (Calymmatobacterium) granulomatis. A 39-year-old female patient with underlying HIV infection presented to the department of dermatology outpatient department with a painless ulcer over the left labia majora for 3 months. Histopathological examination revealed histiocyte which contains granular material resembling coccobacilli and Giemsa staining was positive for Donovan bodies. She was treated with doxycycline 100 mg twice daily and azithromycin 1 g once weekly for 3 weeks and further azithromycin 1 g weekly for the next 9 weeks till complete healing of the lesion. Due to the rarity of this condition in our region, we present this case of donovanosis in an HIV-positive female patient.</p>\",\"PeriodicalId\":44880,\"journal\":{\"name\":\"Indian Journal of Sexually Transmitted Diseases and AIDS\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.6000,\"publicationDate\":\"2024-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11233046/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Indian Journal of Sexually Transmitted Diseases and AIDS\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4103/ijstd.ijstd_62_23\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/6/6 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q4\",\"JCRName\":\"INFECTIOUS DISEASES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Indian Journal of Sexually Transmitted Diseases and AIDS","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/ijstd.ijstd_62_23","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/6/6 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}
A case report of donovanosis in HIV-positive female.
Donovanosis is a chronic granulomatous ulcerative sexually transmitted infection caused by Klebsiella (Calymmatobacterium) granulomatis. A 39-year-old female patient with underlying HIV infection presented to the department of dermatology outpatient department with a painless ulcer over the left labia majora for 3 months. Histopathological examination revealed histiocyte which contains granular material resembling coccobacilli and Giemsa staining was positive for Donovan bodies. She was treated with doxycycline 100 mg twice daily and azithromycin 1 g once weekly for 3 weeks and further azithromycin 1 g weekly for the next 9 weeks till complete healing of the lesion. Due to the rarity of this condition in our region, we present this case of donovanosis in an HIV-positive female patient.