{"title":"结核分枝杆菌的抗药性机制","authors":"M. V. Shulgina","doi":"10.3103/s0891416824700010","DOIUrl":null,"url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Abstract</h3><p>The review presents the results of investigations of the mechanisms of action of long-used and new antituberculosis drugs, and information about new chemical compounds as potential antituberculosis drugs. Data are given on mutations in a number of infectant genes associated with or leading to bacterial resistance to these drugs. The review comprises the results of 67 publications, systematic reviews, and electronic databases.</p>","PeriodicalId":0,"journal":{"name":"","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Mechanisms of Mycobacterium tuberculosis Drug Resistance\",\"authors\":\"M. V. Shulgina\",\"doi\":\"10.3103/s0891416824700010\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<h3 data-test=\\\"abstract-sub-heading\\\">Abstract</h3><p>The review presents the results of investigations of the mechanisms of action of long-used and new antituberculosis drugs, and information about new chemical compounds as potential antituberculosis drugs. Data are given on mutations in a number of infectant genes associated with or leading to bacterial resistance to these drugs. The review comprises the results of 67 publications, systematic reviews, and electronic databases.</p>\",\"PeriodicalId\":0,\"journal\":{\"name\":\"\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0,\"publicationDate\":\"2024-07-09\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://doi.org/10.3103/s0891416824700010\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.3103/s0891416824700010","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Mechanisms of Mycobacterium tuberculosis Drug Resistance
Abstract
The review presents the results of investigations of the mechanisms of action of long-used and new antituberculosis drugs, and information about new chemical compounds as potential antituberculosis drugs. Data are given on mutations in a number of infectant genes associated with or leading to bacterial resistance to these drugs. The review comprises the results of 67 publications, systematic reviews, and electronic databases.