八角生物合成银纳米粒子对变异链球菌的生物活性和抗菌效果：体外研究

2区医学 Q1 Medicine

BMC Complementary and Alternative Medicine Pub Date : 2024-07-10 DOI:10.1186/s12906-024-04550-x

Marwa Aly Elchaghaby, Sayed Rashad, Nada Mohamed Wassef

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引用次数: 0

摘要

银纳米粒子（AgNPs）作为一种可用于预防龋齿的抗菌剂，正受到广泛关注。本研究的目的是调查使用八角茴香生物合成的银纳米粒子对变异链球菌（S.mutans）的生物活性和抗菌效果。研究采用气相色谱-质谱联用技术对八角中的生物活性成分进行了评估。使用鲍尔和柯比的盘扩散机制和最小抑菌浓度评估了八角生物合成银纳米粒子对变异链球菌的抗菌活性。使用八角茴香生物合成的银纳米粒子具有很高的抗氧化活性。AgNPs 可抑制变形杆菌，抑制区直径为 16 毫米，最低抑制浓度为 80 微克/毫升。由八角水提取物生物合成的 AgNPs 似乎是一种潜在而有效的杀菌剂，可用于预防龋齿。

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Bioactivity and antibacterial effect of star anise biosynthesized silver nanoparticles against Streptococcus mutans: an in vitro study

Silver nanoparticles (AgNPs) are receiving a lot of attention as a prospective antibacterial agent for use in caries prevention. The objective of this study was to investigate the bioactivity and antibacterial effect of silver nanoparticles biosynthesized using Star Anise against Streptococcus mutans (S.mutans). The bioactive components of the Star Anise were assessed by employing the gas chromatography-mass spectrometry technique. The antibacterial activities of Star Anise Biosynthesized Silver Nanoparticles against S.mutans bacteria were evaluated using Bauer and Kirby’s disc diffusion mechanism and the minimum inhibitory concentration. Silver nanoparticles biosynthesized using Star Anise revealed high antioxidant activity. AgNPs inhibited S. mutans with a 16 mm inhibition zone diameter and demonstrated an 80 µg/ml minimum inhibitory concentration. Biologically synthesized AgNPs made from aqueous extract of Star anise appear to be a potential and effective bactericidal agent against S.mutans that can be used to prevent dental caries.

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来源期刊

BMC Complementary and Alternative Medicine INTEGRATIVE & COMPLEMENTARY MEDICINE-

CiteScore

7.00

自引率

0.00%

发文量

审稿时长

3 months

期刊介绍： BMC Complementary Medicine and Therapies is an open access journal publishing original peer-reviewed research articles on interventions and resources that complement or replace conventional therapies, with a specific emphasis on research that explores the biological mechanisms of action, as well as their efficacy, safety, costs, patterns of use and/or implementation.