Hyungjoo Park, Misun Kim, Seunghyun Kang, Taewan Kim, Sehyuk Yoon, Jihee Park, Sungjae Ha, Sung Jae Kim
{"title":"通过非均匀区隔增强三维分层微/纳流体系统中的超限电流","authors":"Hyungjoo Park, Misun Kim, Seunghyun Kang, Taewan Kim, Sehyuk Yoon, Jihee Park, Sungjae Ha, Sung Jae Kim","doi":"10.1007/s13206-024-00161-3","DOIUrl":null,"url":null,"abstract":"<p>Overlimiting current (OLC) is a non-linear current response that occurs related to an ion concentration polarization (ICP) phenomenon in micro/nanofluidic systems and holds great importance since it represents the rate of selective ion transportation through perm-selective structure. For last two decades, numerous studies of OLC have been reported about understanding the fundamentals of nanoelectrokinetics and enhancing ion transportation through perm-selective membranes. Recent study reported that the alignment of non-uniform microspace near the perm-selective membranes in two-dimensional micro/nanofluidic systems can significantly enhance OLC, <i>i</i>.<i>e</i>., overlimiting conductance (<i>σ</i><sub>OLC</sub>). This is attributed to recirculation flow induced by combination of unbalanced electroosmosis and induced pressure driven flow among non-uniform microspaces. However, 2D micro/nanofluidic systems have limited practicality due to their small volume and low throughput. Herein, we tested the OLC enhancement using 3D-printed hierarchical micro/nanofluidic systems with respect to the non-uniformity of microspaces. The 3D microspaces were fabricated as a mesh structure using a conventional 3D printer. By comparing current–voltage measurement with each type of mesh, we experimentally confirmed the generation of recirculation flow among non-uniform meshes and ionic current enhancement in 3D hierarchical micro/nanofluidic system. Also, we further investigated the enhancement of overlimiting conductance depending on the mesh pattern. Furthermore, we validated that this effect of microscale non-uniform compartmentalization, both increasing surface area and aligning non-uniform spaces, appears not only at low molar concentration but at high molar concentrations. This demonstration can offer a strategy to design optimal electrochemical systems where a perm-selective ion transportation is crucial.</p>","PeriodicalId":8768,"journal":{"name":"BioChip Journal","volume":"40 1","pages":""},"PeriodicalIF":5.5000,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Enhancement of Overlimiting Current in a Three-Dimensional Hierarchical Micro/Nanofluidic System by Non-uniform Compartmentalization\",\"authors\":\"Hyungjoo Park, Misun Kim, Seunghyun Kang, Taewan Kim, Sehyuk Yoon, Jihee Park, Sungjae Ha, Sung Jae Kim\",\"doi\":\"10.1007/s13206-024-00161-3\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>Overlimiting current (OLC) is a non-linear current response that occurs related to an ion concentration polarization (ICP) phenomenon in micro/nanofluidic systems and holds great importance since it represents the rate of selective ion transportation through perm-selective structure. For last two decades, numerous studies of OLC have been reported about understanding the fundamentals of nanoelectrokinetics and enhancing ion transportation through perm-selective membranes. Recent study reported that the alignment of non-uniform microspace near the perm-selective membranes in two-dimensional micro/nanofluidic systems can significantly enhance OLC, <i>i</i>.<i>e</i>., overlimiting conductance (<i>σ</i><sub>OLC</sub>). This is attributed to recirculation flow induced by combination of unbalanced electroosmosis and induced pressure driven flow among non-uniform microspaces. However, 2D micro/nanofluidic systems have limited practicality due to their small volume and low throughput. Herein, we tested the OLC enhancement using 3D-printed hierarchical micro/nanofluidic systems with respect to the non-uniformity of microspaces. The 3D microspaces were fabricated as a mesh structure using a conventional 3D printer. By comparing current–voltage measurement with each type of mesh, we experimentally confirmed the generation of recirculation flow among non-uniform meshes and ionic current enhancement in 3D hierarchical micro/nanofluidic system. Also, we further investigated the enhancement of overlimiting conductance depending on the mesh pattern. Furthermore, we validated that this effect of microscale non-uniform compartmentalization, both increasing surface area and aligning non-uniform spaces, appears not only at low molar concentration but at high molar concentrations. This demonstration can offer a strategy to design optimal electrochemical systems where a perm-selective ion transportation is crucial.</p>\",\"PeriodicalId\":8768,\"journal\":{\"name\":\"BioChip Journal\",\"volume\":\"40 1\",\"pages\":\"\"},\"PeriodicalIF\":5.5000,\"publicationDate\":\"2024-07-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"BioChip Journal\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://doi.org/10.1007/s13206-024-00161-3\",\"RegionNum\":3,\"RegionCategory\":\"工程技术\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"BIOCHEMICAL RESEARCH METHODS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"BioChip Journal","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1007/s13206-024-00161-3","RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOCHEMICAL RESEARCH METHODS","Score":null,"Total":0}
Enhancement of Overlimiting Current in a Three-Dimensional Hierarchical Micro/Nanofluidic System by Non-uniform Compartmentalization
Overlimiting current (OLC) is a non-linear current response that occurs related to an ion concentration polarization (ICP) phenomenon in micro/nanofluidic systems and holds great importance since it represents the rate of selective ion transportation through perm-selective structure. For last two decades, numerous studies of OLC have been reported about understanding the fundamentals of nanoelectrokinetics and enhancing ion transportation through perm-selective membranes. Recent study reported that the alignment of non-uniform microspace near the perm-selective membranes in two-dimensional micro/nanofluidic systems can significantly enhance OLC, i.e., overlimiting conductance (σOLC). This is attributed to recirculation flow induced by combination of unbalanced electroosmosis and induced pressure driven flow among non-uniform microspaces. However, 2D micro/nanofluidic systems have limited practicality due to their small volume and low throughput. Herein, we tested the OLC enhancement using 3D-printed hierarchical micro/nanofluidic systems with respect to the non-uniformity of microspaces. The 3D microspaces were fabricated as a mesh structure using a conventional 3D printer. By comparing current–voltage measurement with each type of mesh, we experimentally confirmed the generation of recirculation flow among non-uniform meshes and ionic current enhancement in 3D hierarchical micro/nanofluidic system. Also, we further investigated the enhancement of overlimiting conductance depending on the mesh pattern. Furthermore, we validated that this effect of microscale non-uniform compartmentalization, both increasing surface area and aligning non-uniform spaces, appears not only at low molar concentration but at high molar concentrations. This demonstration can offer a strategy to design optimal electrochemical systems where a perm-selective ion transportation is crucial.
期刊介绍:
BioChip Journal publishes original research and reviews in all areas of the biochip technology in the following disciplines, including protein chip, DNA chip, cell chip, lab-on-a-chip, bio-MEMS, biosensor, micro/nano mechanics, microfluidics, high-throughput screening technology, medical science, genomics, proteomics, bioinformatics, medical diagnostics, environmental monitoring and micro/nanotechnology. The Journal is committed to rapid peer review to ensure the publication of highest quality original research and timely news and review articles.