Mpox诱发的直肠炎。

HCA healthcare journal of medicine Pub Date : 2024-04-30 eCollection Date: 2024-01-01 DOI:10.36518/2689-0216.1585
Saif Ghias, Niyati Joshi, Dzenana Cabaravdic, Ramesh Nathan, Jasprit Takher
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引用次数: 0

摘要

简介:痘病毒(Mpox)以前被称为猴痘,是一种人畜共患病病毒,属于正痘病毒属(Orthopoxvirus),潜伏期长短不一,症状多种多样。虽然痘病毒感染者会出现全身病毒性前驱症状,但也会出现直肠炎等非典型症状。与麻风腮相关的直肠炎是一种相对少见的初期症状,据报道发病率为 14-32.9%,自 2022 年全球流行以来,发病率有所上升:我们介绍了一例确诊的肛门直肠混合痘病例,患者为一名 27 岁男性,3 天来出现间歇性肛门直肠出血,并伴有处于不同愈合阶段的各种形式的皮肤损伤。症状出现前 8 天,他在纽约进行了无保护性交,而纽约当时是该疾病的流行中心。计算机断层扫描成像显示直肠增厚并伴有淋巴结肿大,与急性直肠炎的检查结果一致:本病例报告旨在确认 Mpox 病毒的流行。自麻疹流行以来,麻疹病例的增加导致了更多的并发症,这些并发症已被公共卫生专家发现并进行了研究。虽然这种病毒与其他病毒一样表现为全身性前驱症状,但这些独特的胃肠道表现和发现可能是识别这种感染的第一步,并确保在未来流行病来临时能够迅速治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Mpox-Induced Proctitis.

Introduction: Mpox, formerly known as monkeypox, is a zoonotic virus in the genus Orthopoxvirus, which has a variable incubation period and an extensive array of symptoms. While those infected with Mpox have displayed generalized viral prodromal symptoms, atypical symptoms such as proctitis have also been seen. Proctitis associated with Mpox is a relatively infrequent initial presenting symptom with a reported incidence of 14-32.9% that has seen an uptick in prevalence since the 2022 global endemic.

Case presentation: We present a confirmed case of Mpox in a 27-year-old male who presented with 3 days of intermittent anorectal bleeding and various forms of cutaneous lesions at different stages of healing. He had engaged in unprotected sexual intercourse 8 days prior to the onset of his symptoms in New York, which at the time was the epicenter of the endemic. Computed tomography imaging showed thickening of the rectum with associated lymphadenopathy, consistent with findings of acute proctitis.

Conclusion: The intent of this case report is to acknowledge the prevalence of the Mpox virus. Since the endemic, increased cases of Mpox have led to more complications that have been identified and studied by public health experts. The complication of proctitis due to Mpox in a certain subset of patients is important to fully understand that while this virus presents with a generalized prodrome like other viruses, these unique gastrointestinal presentations and findings may be the first step in identifying this infection and ensuring rapid treatment if future endemics arrive.

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