减少每日氧化镁剂量对通便效果的影响:一项单中心回顾性研究。

Norio Watanabe, Akira Itano, Motozumi Ando, Masami Kawahara
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引用次数: 0

摘要

研究目的研究在保持大便通畅患者每日氧化镁(MgO)总剂量不变的情况下,减少氧化镁(MgO)的服用次数所产生的通便效果。患者和方法:这项回顾性分析涉及 11 名排便规律的患者,他们在入住护理机构后因便秘被处方氧化镁,并由药剂师陪同进行家访。这项调查是在两周内将每日剂量从三次减为两次或从两次减为一次之前和之后进行的。结果显示改变服药次数前后两周的排便次数分别为 7.6 ± 3.4 次和 6.6 ± 4.0 次。差异无统计学意义(P=0.09)。布里斯托粪便形态量表在改变频率前后两周分别为 3.9 ± 0.9 和 4.0 ± 0.9,差异无统计学意义(P=0.93)。改变方案两周后,氧化镁方案保持不变,也没有按需使用泻药。结论结果表明,减少氧化镁的每日剂量并不会影响其通便作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effect of reduced daily magnesium oxide doses on laxative effect: a single-center retrospective study.

Objective: To investigate the laxative effect of reducing the number of daily doses of magnesium oxide (MgO), while maintaining the total daily dose of MgO in patients with good bowel movements. Patients and Methods: The retrospective analysis involved 11 patients with regular bowel movements who were prescribed MgO for constipation upon admission to a nursing care facility accompanied by home visits by a pharmacist. This investigation was conducted before and after reducing the number of daily doses from three to two, or from two to one, over a two-week period. Results: The number of bowel movements was 7.6 ± 3.4 and 6.6 ± 4.0 times for two weeks before and after the change in dosage frequency, respectively. The difference was not statistically significant (P=0.09). The Bristol Stool Form Scale was 3.9 ± 0.9 and 4.0 ± 0.9 two weeks before and after the change, respectively, which was not significant (P=0.93). Two weeks after the change, the MgO regimen remained unchanged and no on-demand laxatives were administered. Conclusions: The results suggest that reducing the number of daily doses of MgO does not affect its laxative action.

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