Ana Vitoria Lima de Paula , Gabrielly Menin Dykstra , Rebeca Barbosa da Rocha , Alessandra Tanuri Magalhães , Baldomero Antônio Kato da Silva , Vinicius Saura Cardoso
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引用次数: 0
摘要
本系统综述旨在探讨 1 型和 2 型糖尿病(DM)患者的糖尿病周围神经病变(DPN)与心脏自主神经病变(CAN)之间的关系:系统综述遵循在 Prospero(CRD42020182899)上注册的协议。两位作者独立检索了 PubMed、Scopus、Embase、Cochrane 和 Web of Science 数据库。不一致之处由第三位作者解决。综述包括调查DM患者CAN与DPN之间关系的观察性研究:最初,在 1165 项研究中,只有 16 项被选中,其中 42.8% 的研究涉及患有一种类型糖尿病的志愿者,14.3% 的研究涉及两种类型糖尿病,14.3% 的研究未指明类型。志愿者总人数为 2582 人,大部分为 2 型糖尿病患者。分析结果表明,CAN 与 DPN 之间存在关系。据观察,更严重的 DPN 与更差的自律神经测试结果有关。一些研究表明,评估 DPN 的技术可能是导致 CAN 的风险因素:本综述介绍了 DPN 和 CAN 之间可能存在的关系,例如两者的严重程度。
The association of diabetic peripheral neuropathy with cardiac autonomic neuropathy in individuals with diabetes mellitus: A systematic review
This systematic review aimed to explore the relationship between diabetic peripheral neuropathy (DPN) and cardiac autonomic neuropathy (CAN) in individuals with type 1 and 2 diabetes mellitus (DM). Methods: The systematic review follow the protocol registered in Prospero (CRD42020182899). Two authors independently searched the PubMed, Scopus, Embase, Cochrane, and Web of Science databases. Discrepancies were resolved by a third author. The review included observational studies investigating the relationship between CAN and DPN in individuals with DM. Results: Initially, out of 1165 studies, only 16 were selected, with 42.8 % involving volunteers with one type of diabetes, 14.3 % with both types of diabetes and 14.3 % not specify the type. The total number of volunteers was 2582, mostly with type 2 DM. It was analyzed that there is a relationship between CAN and DPN. It was observed that more severe levels of DPN are associated with worse outcomes in autonomic tests. Some studies suggested that the techniques for evaluating DPN might serve as risk factors for CAN. Conclusion: The review presents a possible relationship between DPN and CAN, such as in their severity.
期刊介绍:
Journal of Diabetes and Its Complications (JDC) is a journal for health care practitioners and researchers, that publishes original research about the pathogenesis, diagnosis and management of diabetes mellitus and its complications. JDC also publishes articles on physiological and molecular aspects of glucose homeostasis.
The primary purpose of JDC is to act as a source of information usable by diabetes practitioners and researchers to increase their knowledge about mechanisms of diabetes and complications development, and promote better management of people with diabetes who are at risk for those complications.
Manuscripts submitted to JDC can report any aspect of basic, translational or clinical research as well as epidemiology. Topics can range broadly from early prediabetes to late-stage complicated diabetes. Topics relevant to basic/translational reports include pancreatic islet dysfunction and insulin resistance, altered adipose tissue function in diabetes, altered neuronal control of glucose homeostasis and mechanisms of drug action. Topics relevant to diabetic complications include diabetic retinopathy, neuropathy and nephropathy; peripheral vascular disease and coronary heart disease; gastrointestinal disorders, renal failure and impotence; and hypertension and hyperlipidemia.