Sentinel cerebral embolic protection device deployment in aberrant right subclavian artery via left radial artery access

Procedure-related stroke represents a major complication of transcatheter aortic valve replacement (TAVR). The Sentinel Cerebral Protection System is the only FDA-approved embolic protection device for TAVR and is intended for use via right radial access. As TAVR has become the preferred modality for aortic valve replacement, protection devices like Sentinel have been developed to reduce procedural complications; however, its use in aberrant aortic arch anatomy has not been previously reported. We present a case of successful Sentinel deployment and embolic protection via alternative left radial artery access in a patient with an aberrant right subclavian artery.