利用 scRNA-seq 数据中的原始计数矩阵进行单细胞 RNA 注释的机器学习、统计方法和人工智能研究进展

Megha Patel, Nimish Magre, Himanshi Motwani, Nik Bear Brown
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摘要

单细胞 RNA 测序(scRNA-seq)彻底改变了我们以单个细胞为单位分析基因表达的能力,为我们深入了解细胞异质性和复杂的生物系统提供了前所未有的视角。本文回顾了为分析 scRNA-seq 数据而量身定制的各种先进计算和机器学习技术,强调了它们在数据处理管道不同阶段的作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Advances in Machine Learning, Statistical Methods, and AI for Single-Cell RNA Annotation Using Raw Count Matrices in scRNA-seq Data
Single-cell RNA sequencing (scRNA-seq) has revolutionized our ability to analyze gene expression at the resolution of individual cells, providing unprecedented insights into cellular heterogeneity and complex biological systems. This paper reviews various advanced computational and machine learning techniques tailored for the analysis of scRNA-seq data, emphasizing their roles in different stages of the data processing pipeline.
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