镍光氧化催化烯基卤化物和苯酚的 E 和 Z 立体转化偶联反应

IF 1.4 4区化学 Q3 CHEMISTRY, MULTIDISCIPLINARY

Chemistry Letters Pub Date : 2024-06-25 DOI:10.1093/chemle/upae111

Sodai Nishino, Takuya Kurahashi

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引用次数: 0

摘要

在此，我们报告了一种镍光氧化催化的苯酚与烯基卤化物的立体转化偶联反应，该反应可产生 Z 偶联产物。此外，只需改变溶剂，该反应还能以高立体选择性获得 E-偶联产物。研究发现，改变产物立体异构体的关键因素是光催化剂的荧光寿命。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Nickel-photoredox-catalyzed E- and Z-stereoconvergent coupling of alkenyl halides and phenols

Herein, we report a Ni-photoredox-catalyzed stereoconvergent coupling of phenols and alkenyl halides, which affords a Z-coupling product. Moreover, by simply changing the solvent, the reaction also provides access to the E-coupling product with high stereoselectivity. The key factor for changing the stereoisomer of the product was found to be the fluorescence lifetime of photocatalyst.

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来源期刊

Chemistry Letters 化学-化学综合

CiteScore

3.00

自引率

6.20%

发文量

260

审稿时长

1.2 months

期刊介绍： Chemistry Letters covers the following topics: -Organic Chemistry- Physical Chemistry- Inorganic Chemistry- Analytical Chemistry- Materials Chemistry- Polymer Chemistry- Supramolecular Chemistry- Organometallic Chemistry- Coordination Chemistry- Biomolecular Chemistry- Natural Products and Medicinal Chemistry- Electrochemistry