异氰酸酯及相关化合物的研究。通过新型三组分反应合成 3-取代的 2-芳磺酰氨基-3,4-二氢-4-氧代喹唑类化合物

IF 2 3区 化学 Q2 CHEMISTRY, ORGANIC
Ricardo Bossio, Stefano Marcaccini, Roberto Pepino
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引用次数: 0

摘要

在苄基三乙基氯化铵存在下,异氰酸酯 1、蒽酸甲酯(2)和氯胺 T(3a)或氯胺 B(3b)很容易发生反应,生成胍类化合物 4,加热后发生闭环反应,生成标题化合物 5。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Studies on Isocyanides and Related Compounds. Synthesis of 3‐Substituted 2‐Arylsulfonylamino‐3,4‐dihydro‐4‐oxoquinazolines via a Novel Three‐Component Reaction
The reaction between isocyanides 1,methyl anthranilate (2) and chloramines T (3a) or chloramines B (3b) occurred easily, in the presence of benzyltriethylammonium chloride to give the guanidines 4 which, upon heating, underwent a ring‐closure reaction to afford the title compounds 5.
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来源期刊
Journal of Heterocyclic Chemistry
Journal of Heterocyclic Chemistry 化学-有机化学
CiteScore
5.20
自引率
4.20%
发文量
177
审稿时长
3.9 months
期刊介绍: The Journal of Heterocyclic Chemistry is interested in publishing research on all aspects of heterocyclic chemistry, especially development and application of efficient synthetic methodologies and strategies for the synthesis of various heterocyclic compounds. In addition, Journal of Heterocyclic Chemistry promotes research in other areas that contribute to heterocyclic synthesis/application, such as synthesis design, reaction techniques, flow chemistry and continuous processing, multiphase catalysis, green chemistry, catalyst immobilization and recycling.
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