美沙酮维持治疗患者不坚持治疗及其相关因素:越南一项多中心横断面研究。

IF 4 2区 社会学 Q1 SUBSTANCE ABUSE
Huong Thi Thanh Nguyen, Dai Xuan Dinh
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引用次数: 0

摘要

目的:这项多中心横断面研究调查了越南美沙酮维持治疗患者不坚持治疗的普遍程度及其相关因素:这项多中心横断面研究旨在调查越南美沙酮维持治疗患者不坚持治疗的普遍性及其相关因素:这项二级数据分析是利用之前一项研究的数据进行的。对 600 名患者进行了面对面访谈,以收集他们的人口统计特征和社会支持数据。有关治疗特点和患者不坚持治疗的信息来自医疗记录和监测其治疗过程的书籍。不坚持治疗的定义是在过去三个月中至少漏服一次美沙酮:不坚持治疗的总发生率为 45.7%。完全坚持治疗的患者的社会支持平均得分明显高于未坚持治疗的患者(P 结论:未坚持治疗的患者的社会支持平均得分明显高于未坚持治疗的患者:在越南美沙酮维持治疗患者中,不坚持治疗的比例很高。需要采取涉及社会支持、职业、收入和教育的干预措施来改善他们的治疗依从性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Treatment non-adherence among methadone maintenance patients and associated factors: a multicenter, cross-sectional study in Vietnam.

Objective: This multicenter, cross-sectional study was conducted to investigate the prevalence of treatment non-adherence and its associated factors among methadone maintenance patients in Vietnam.

Methods: This secondary data analysis was conducted using the data from a previous study. Six hundred patients were interviewed face-to-face to collect data on their demographic characteristics and social support. Information about the treatment characteristics and patients' non-adherence was gathered from medical records and books monitoring their treatment process. Treatment non-adherence was defined as missing at least one methadone dose in the last three months.

Results: The overall prevalence of non-adherence was 45.7%. The average social support score of patients who completely adhered to treatment was significantly higher than that of those who did not (p < 0.001). In the multivariate logistic regression model, for each one-unit increase in social support (one score), treatment time (a year), and patient's monthly income (one million Vietnam dongs), the odds of non-adherence decreased by 28% (aOR = 0.72, 95%CI 0.59-0.88, p = 0.002), 15% (aOR = 0.85, 95%CI 0.80-0.91, p < 0.001) and 9% (aOR = 0.91, 95%CI 0.85-0.97, p = 0.004), respectively. Patients living in Son La (a mountainous province) were 1.72 times (95%CI 1.09-2.71) more likely to be non-adherent as compared to those in other areas (p = 0.020). As per univariate analyses, other associated factors could be age, education level, family monthly income, occupation, and opioid relapse (p < 0.001).

Conclusions: A high non-adherence rate was found among Vietnamese methadone maintenance patients. Interventions involving social support, occupation, income, and education are needed to improve their treatment adherence.

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来源期刊
Harm Reduction Journal
Harm Reduction Journal Medicine-Public Health, Environmental and Occupational Health
CiteScore
5.90
自引率
9.10%
发文量
126
审稿时长
26 weeks
期刊介绍: Harm Reduction Journal is an Open Access, peer-reviewed, online journal whose focus is on the prevalent patterns of psychoactive drug use, the public policies meant to control them, and the search for effective methods of reducing the adverse medical, public health, and social consequences associated with both drugs and drug policies. We define "harm reduction" as "policies and programs which aim to reduce the health, social, and economic costs of legal and illegal psychoactive drug use without necessarily reducing drug consumption". We are especially interested in studies of the evolving patterns of drug use around the world, their implications for the spread of HIV/AIDS and other blood-borne pathogens.
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