在阴道镜筛查宫颈癌前病变和恶性病变时，改良斯韦德阴道镜指数与改良雷德指数的比较：横断面分析。

Q3 Medicine

Cancer treatment and research communications Pub Date : 2024-01-01 DOI:10.1016/j.ctarc.2024.100828

Dr. Swati Priya , Dr. Amiy Arnav , Dr. Swati Mittal , Dr. Pammy Pravina , Dr Suhagini Murmu , Dr. Gauri Gandhi

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引用次数: 0

摘要

背景：印度的宫颈癌病例占全世界的四分之一。阴道镜检查用于评估筛查结果异常的妇女的宫颈。为实现报告的标准化，引入了各种评分标准，其中里德阴道镜指数（RCI）和瑞典评分标准最为常用：本研究旨在确定新引入的 MSCI 的诊断效果和临床相关性，并比较 MSCI 和修正版 Reid 指数。在阴道镜诊断 CIN 2 或更高病变时，MSCI 评分 9 分表现最佳。阈值 9 对 CIN 2 或以上病变的敏感性、特异性、PPV 和 NPV 分别为 94.92%、67.88%、51.38% 和 97.39%。修正里德指数阈值 3 在检测 CIN 2 或更高病变方面表现最佳，其敏感性、特异性、PPV 和 NPV 分别为 84.75 %、44.85 %、35.46 % 和 89.16 %。在比较 MSCI 和核磁共振成像的曲线下面积（AUC）时，我们发现 MSCI（0.854）和改良里德指数（0.657）的曲线下面积差异显著（P < 0.05）：结论：MSCI 在诊断 HGL 和 LGL 或以上时的表现优于改良 Reid 指数。此外，与瑞典评分或改良雷德指数相比，MSCI省略了不实用的测量方法，纳入了更简单实用的参数，因此是一种简单有效的筛查工具。

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Modified swede colposcopic index versus modified reid index in colposcopic screening for premalignant & malignant lesions of the cervix: a cross-sectional analysis

Background

Cervical cancer cases in India account for one-fourth of the worldwide burden. Colposcopy is used to evaluate the cervix of women with abnormal screening test results. For standardized reporting, various scores were introduced of those, Reid Colposcopic Index (RCI) and Swede score are the most commonly used.

Aims and Objectives

This study is undertaken to determine the diagnostic efficacy and clinical relevance of the newly introduced MSCI and compare MSCI and Modified Reid Index.

Results

225 women out of 237 were analyzed. MSCI score 9 perform best for colposcopic diagnosis of CIN 2 or higher lesions. The sensitivity, specificity, PPV, and NPV for threshold score 9 for CIN 2 or higher lesions were 94.92 %, 67.88 %, 51.38 %, and 97.39 % respectively. Modified Reid Index threshold 3 performed best for the detection of CIN 2 or higher lesions with a sensitivity, specificity, PPV, and NPV of 84.75 %, 44.85 %, 35.46 %, and 89.16 % respectively. On comparing the area under the curve (AUC) for MSCI and MRI, we found that the difference between the AUC of MSCI (0.854) and Modified Reid Index (0.657) was significant (P < 0.05).

Conclusion

MSCI performs better than the modified reid index for the diagnosis of both HGL and LGL or higher. Also, the omission of impractical measurements and inclusion of easier and more practical parameters than the Swede score or Modified Reid Index makes MSCI a simple and effective screening tool

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来源期刊

Cancer treatment and research communications Medicine-Oncology

CiteScore

4.30

自引率

0.00%

发文量

148

审稿时长

56 days

期刊介绍： Cancer Treatment and Research Communications is an international peer-reviewed publication dedicated to providing comprehensive basic, translational, and clinical oncology research. The journal is devoted to articles on detection, diagnosis, prevention, policy, and treatment of cancer and provides a global forum for the nurturing and development of future generations of oncology scientists. Cancer Treatment and Research Communications publishes comprehensive reviews and original studies describing various aspects of basic through clinical research of all tumor types. The journal also accepts clinical studies in oncology, with an emphasis on prospective early phase clinical trials. Specific areas of interest include basic, translational, and clinical research and mechanistic approaches; cancer biology; molecular carcinogenesis; genetics and genomics; stem cell and developmental biology; immunology; molecular and cellular oncology; systems biology; drug sensitivity and resistance; gene and antisense therapy; pathology, markers, and prognostic indicators; chemoprevention strategies; multimodality therapy; cancer policy; and integration of various approaches. Our mission is to be the premier source of relevant information through promoting excellence in research and facilitating the timely translation of that science to health care and clinical practice.