GLP-1 激动剂会影响情绪：一例服用 Ozempic（赛马鲁肽）后抑郁加重的病例。

Q3 Medicine

Innovations in clinical neuroscience Pub Date : 2024-06-01 eCollection Date: 2024-04-01

Senthil Vel Rajan Rajaram Manoharan, Rohit Madan

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引用次数: 0

摘要

胰高血糖素样肽-1（GLP-1）受体激动剂在糖尿病治疗中备受关注，它们通过模仿 GLP-1 的作用发挥作用，GLP-1 是一种调节胰岛素分泌和食欲的激素。虽然这些药物越来越受欢迎，但由于数据不一致，它们对情绪和其他精神表现的影响仍不确定。有研究表明，胰高血糖素会影响涉及情绪调节的大脑区域。本病例报告强调了可能与塞马鲁肽有关的不良情绪变化，以及在这一领域开展进一步研究的必要性。

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GLP-1 Agonists Can Affect Mood: A Case of Worsened Depression on Ozempic (Semaglutide).

Glucagon-like peptide-1 (GLP-1) receptor agonists have garnered significant attention in diabetes management, and they act by mimicking the effects of GLP-1, a hormone that regulates insulin secretion and appetite. While these medications have become increasingly popular, their impact on mood and other psychiatric manifestations remains uncertain because of inconsistent data. It has been shown to affect brain regions involved in emotional regulation. This case report underscores the adverse mood changes possibly linked to semaglutide and the need for further study in this area.

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来源期刊

Innovations in clinical neuroscience Medicine-Psychiatry and Mental Health

CiteScore

2.10

自引率

0.00%

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