CAR-T 中的凝血病变：关键问题还是昙花一现？

IF 5.1 2区医学 Q1 HEMATOLOGY

British Journal of Haematology Pub Date : 2024-06-28 DOI:10.1111/bjh.19619

Eugenio Galli, Federica Sorà, Elena Rossi

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引用次数: 0

摘要

尽管 Peng 及其同事对 CAR-T 相关凝血病的临床和实验室方面进行了广泛的综述，但目前的文献在术语和分级方面往往缺乏特异性，凝血病的临床意义可能仍不明确。仍需就分层和预防提出明确的建议，以规范这一主题的临床方法。相关评论血液恶性肿瘤 CAR-T 疗法相关凝血异常：综述。Doi: 10.1111/bjh.19583.

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Coagulopathy in CAR-T: Critical concern or mere blip?

Despite Peng and colleagues providing an extensive review of the clinical and laboratory aspects of CAR-T-associated coagulopathy, the current literature often lacks specificity in nomenclature and gradings, and the clinical implications of coagulopathy may remain unclear. Clear recommendations on stratification and prophylaxis are still required to standardize the clinical approach to this topic.

Commentary on: Peng et al. Coagulation abnormalities associated with CAR-T therapy in hematological malignancies: A review. Br J Haematol 2024;205:420-428.

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来源期刊

British Journal of Haematology 医学-血液学

CiteScore

8.60

自引率

4.60%

发文量

565

审稿时长

1 months

期刊介绍： The British Journal of Haematology publishes original research papers in clinical, laboratory and experimental haematology. The Journal also features annotations, reviews, short reports, images in haematology and Letters to the Editor.