M Tamilarasi, S Kumarganesh, K Martin Sagayam, J Andrew
{"title":"利用 UNet 卷积神经网络方法和非子采样剪切力变换检测和分割胶质瘤肿瘤","authors":"M Tamilarasi, S Kumarganesh, K Martin Sagayam, J Andrew","doi":"10.1089/cmb.2023.0339","DOIUrl":null,"url":null,"abstract":"<p><p>The prompt and precise identification and delineation of tumor regions within glioma brain images are critical for mitigating the risks associated with this life-threatening ailment. In this study, we employ the UNet convolutional neural network (CNN) architecture for glioma tumor detection. Our proposed methodology comprises a transformation module, a feature extraction module, and a tumor segmentation module. The spatial domain representation of brain magnetic resonance imaging images undergoes decomposition into low- and high-frequency subbands via a non-subsampled shearlet transform. Leveraging the selective and directive characteristics of this transform enhances the classification efficacy of our proposed system. Shearlet features are extracted from both low- and high-frequency subbands and subsequently classified using the UNet-CNN architecture to identify tumor regions within glioma brain images. We validate our proposed glioma tumor detection methodology using publicly available datasets, namely Brain Tumor Segmentation (BRATS) 2019 and The Cancer Genome Atlas (TCGA). The mean classification rates achieved by our system are 99.1% for the BRATS 2019 dataset and 97.8% for the TCGA dataset. Furthermore, our system demonstrates notable performance metrics on the BRATS 2019 dataset, including 98.2% sensitivity, 98.7% specificity, 98.9% accuracy, 98.7% intersection over union, and 98.5% disc similarity coefficient. Similarly, on the TCGA dataset, our system achieves 97.7% sensitivity, 98.2% specificity, 98.7% accuracy, 98.6% intersection over union, and 98.4% disc similarity coefficient. Comparative analysis against state-of-the-art methods underscores the efficacy of our proposed glioma brain tumor detection approach.</p>","PeriodicalId":15526,"journal":{"name":"Journal of Computational Biology","volume":" ","pages":"757-768"},"PeriodicalIF":1.4000,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Detection and Segmentation of Glioma Tumors Utilizing a UNet Convolutional Neural Network Approach with Non-Subsampled Shearlet Transform.\",\"authors\":\"M Tamilarasi, S Kumarganesh, K Martin Sagayam, J Andrew\",\"doi\":\"10.1089/cmb.2023.0339\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The prompt and precise identification and delineation of tumor regions within glioma brain images are critical for mitigating the risks associated with this life-threatening ailment. In this study, we employ the UNet convolutional neural network (CNN) architecture for glioma tumor detection. Our proposed methodology comprises a transformation module, a feature extraction module, and a tumor segmentation module. The spatial domain representation of brain magnetic resonance imaging images undergoes decomposition into low- and high-frequency subbands via a non-subsampled shearlet transform. Leveraging the selective and directive characteristics of this transform enhances the classification efficacy of our proposed system. Shearlet features are extracted from both low- and high-frequency subbands and subsequently classified using the UNet-CNN architecture to identify tumor regions within glioma brain images. We validate our proposed glioma tumor detection methodology using publicly available datasets, namely Brain Tumor Segmentation (BRATS) 2019 and The Cancer Genome Atlas (TCGA). The mean classification rates achieved by our system are 99.1% for the BRATS 2019 dataset and 97.8% for the TCGA dataset. Furthermore, our system demonstrates notable performance metrics on the BRATS 2019 dataset, including 98.2% sensitivity, 98.7% specificity, 98.9% accuracy, 98.7% intersection over union, and 98.5% disc similarity coefficient. Similarly, on the TCGA dataset, our system achieves 97.7% sensitivity, 98.2% specificity, 98.7% accuracy, 98.6% intersection over union, and 98.4% disc similarity coefficient. Comparative analysis against state-of-the-art methods underscores the efficacy of our proposed glioma brain tumor detection approach.</p>\",\"PeriodicalId\":15526,\"journal\":{\"name\":\"Journal of Computational Biology\",\"volume\":\" \",\"pages\":\"757-768\"},\"PeriodicalIF\":1.4000,\"publicationDate\":\"2024-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Computational Biology\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://doi.org/10.1089/cmb.2023.0339\",\"RegionNum\":4,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/6/27 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q4\",\"JCRName\":\"BIOCHEMICAL RESEARCH METHODS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Computational Biology","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1089/cmb.2023.0339","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/6/27 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"BIOCHEMICAL RESEARCH METHODS","Score":null,"Total":0}
Detection and Segmentation of Glioma Tumors Utilizing a UNet Convolutional Neural Network Approach with Non-Subsampled Shearlet Transform.
The prompt and precise identification and delineation of tumor regions within glioma brain images are critical for mitigating the risks associated with this life-threatening ailment. In this study, we employ the UNet convolutional neural network (CNN) architecture for glioma tumor detection. Our proposed methodology comprises a transformation module, a feature extraction module, and a tumor segmentation module. The spatial domain representation of brain magnetic resonance imaging images undergoes decomposition into low- and high-frequency subbands via a non-subsampled shearlet transform. Leveraging the selective and directive characteristics of this transform enhances the classification efficacy of our proposed system. Shearlet features are extracted from both low- and high-frequency subbands and subsequently classified using the UNet-CNN architecture to identify tumor regions within glioma brain images. We validate our proposed glioma tumor detection methodology using publicly available datasets, namely Brain Tumor Segmentation (BRATS) 2019 and The Cancer Genome Atlas (TCGA). The mean classification rates achieved by our system are 99.1% for the BRATS 2019 dataset and 97.8% for the TCGA dataset. Furthermore, our system demonstrates notable performance metrics on the BRATS 2019 dataset, including 98.2% sensitivity, 98.7% specificity, 98.9% accuracy, 98.7% intersection over union, and 98.5% disc similarity coefficient. Similarly, on the TCGA dataset, our system achieves 97.7% sensitivity, 98.2% specificity, 98.7% accuracy, 98.6% intersection over union, and 98.4% disc similarity coefficient. Comparative analysis against state-of-the-art methods underscores the efficacy of our proposed glioma brain tumor detection approach.
期刊介绍:
Journal of Computational Biology is the leading peer-reviewed journal in computational biology and bioinformatics, publishing in-depth statistical, mathematical, and computational analysis of methods, as well as their practical impact. Available only online, this is an essential journal for scientists and students who want to keep abreast of developments in bioinformatics.
Journal of Computational Biology coverage includes:
-Genomics
-Mathematical modeling and simulation
-Distributed and parallel biological computing
-Designing biological databases
-Pattern matching and pattern detection
-Linking disparate databases and data
-New tools for computational biology
-Relational and object-oriented database technology for bioinformatics
-Biological expert system design and use
-Reasoning by analogy, hypothesis formation, and testing by machine
-Management of biological databases