饮水中 ALDH2 的肠道-肝脏高速公路

IF 18.9 1区医学 Q1 ENDOCRINOLOGY & METABOLISM

Nature metabolism Pub Date : 2024-06-20 DOI:10.1038/s42255-024-01071-2

Subhash C. Pandey, Emir Malovic

引用次数: 0

摘要

在本期《自然-新陈代谢》（Nature Metabolism）杂志上，Fu 等人的研究表明，同时在肠道和肝脏中遗传性缺失醛脱氢酶 2 (ALDH2)可协同调节乙醛 (AcH) 水平和酒精消耗量。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Gut–liver highway of ALDH2 in drinking

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Gut–liver highway of ALDH2 in drinking

In this issue of Nature Metabolism, Fu et al. show that genetic deletion of aldehyde dehydrogenase 2 (ALDH2) simultaneously in the gut and liver synergistically regulates acetaldehyde (AcH) levels and alcohol consumption.

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来源期刊

Nature metabolism ENDOCRINOLOGY & METABOLISM-

CiteScore

27.50

自引率

2.40%

发文量

170

期刊介绍： Nature Metabolism is a peer-reviewed scientific journal that covers a broad range of topics in metabolism research. It aims to advance the understanding of metabolic and homeostatic processes at a cellular and physiological level. The journal publishes research from various fields, including fundamental cell biology, basic biomedical and translational research, and integrative physiology. It focuses on how cellular metabolism affects cellular function, the physiology and homeostasis of organs and tissues, and the regulation of organismal energy homeostasis. It also investigates the molecular pathophysiology of metabolic diseases such as diabetes and obesity, as well as their treatment. Nature Metabolism follows the standards of other Nature-branded journals, with a dedicated team of professional editors, rigorous peer-review process, high standards of copy-editing and production, swift publication, and editorial independence. The journal has a high impact factor, has a certain influence in the international area, and is deeply concerned and cited by the majority of scholars.