基于 fMRI 的踝关节肌肉干针对大脑活动图的影响:随机对照试验的研究方案。

IF 0.9 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE
Roshanak Honarpishe, Soofia Naghdi, Noureddin Nakhostin Ansari, Jan Dommerholt, Marzieh Hassanabadi
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引用次数: 0

摘要

重要性:神经调节可能是干针疗法(DN)的基本机制之一,但其机制尚未完全明确:本随机对照试验旨在利用功能磁共振成像(fMRI)评估干针刺激慢性踝关节不稳(CAI)和健康受试者胫骨前肌和腓肠肌的效果:设计:符合 SPIRIT 标准的临床研究方案:地点:脑图实验室:本研究将包括 30 名年龄在 18 至 40 岁之间的参与者。20 名健康参与者将被随机分为两组(真实 DN 组和假 DN 组)。第三组还将招募 10 名 CAI 患者,他们只接受真实 DN 进行比较:主要结果和测量:主要结果和测量:体素计数、峰值激活坐标和峰值强度将作为报告脑图激活的主要结果。测量将在 DN 治疗前、治疗中和治疗后进行。踝关节背屈肌的力量、主动背屈运动范围和麦吉尔疼痛问卷短表将作为次要结果测量指标:这项研究的结果将在同行评审期刊上发表,并在国内和国际大会上发表演讲:本试验将探索健康参与者大脑对真实和虚假 DN 的反应,以及 CAI 患者大脑对真实 DN 的反应。总之,我们的结果将为 DN 的神经机制提供初步证据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Effect of Ankle Muscles Dry Needling on Brain Activity Map Based on fMRI: a Study Protocol for Randomized Controlled Trial.

Importance: Neuromodulation may be one of the underlying mechanisms of dry needling (DN); however, the mechanism has not yet been fully clarified.

Objective: This randomized controlled trial is designed to evaluate DN stimulation of the tibialis anterior and peroneus longus muscles in chronic ankle instability (CAI) and healthy subjects, employing functional magnetic resonance imaging (fMRI).

Design: Clinical study protocol, SPIRIT compliant.

Setting: Brain Mapping Laboratory.

Population: A total of thirty participants aged between 18 and 40 years old will be included in this study. Twenty healthy participants will be randomized into 2 groups (real DN and sham DN). Ten patients with CAI will also be recruited to the third group and receive only real DN for comparison.

Exposures: Real and sham DN.

Main outcomes and measures: The voxel count, coordinates of peak activation, and peak intensity will be obtained as primary outcomes to report brain map activation. Measurements will be taken before, during, and after DN treatment. The strength of the ankle dorsiflexors, active dorsiflexion range of motion, and McGill pain questionnaire short-form will be used as secondary outcome measures.

Results: The results from this study will be published in peer-reviewed journals and disseminated as presentations at national and international congresses.

Conclusion: This trial will explore brain responses to real and sham DN in healthy participants and to real DN in CAI patients. Overall, our results will provide preliminary evidence of the neural mechanism of DN.

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来源期刊
Journal of Acupuncture and Meridian Studies
Journal of Acupuncture and Meridian Studies INTEGRATIVE & COMPLEMENTARY MEDICINE-
CiteScore
1.50
自引率
10.00%
发文量
35
审稿时长
12 weeks
期刊介绍: The Journal of Acupuncture and Meridian Studies is a quarterly, peer-reviewed journal featuring high-quality studies related to basic and clinical acupuncture and meridian research. It also includes new paradigm of integrative research, covering East–West and traditional–modern medicine. Manuscripts should fall into one of the categories: topical review, original research paper, brief ... click here for full Aims & Scope The Journal of Acupuncture and Meridian Studies is a quarterly, peer-reviewed journal featuring high-quality studies related to basic and clinical acupuncture and meridian research. It also includes new paradigm of integrative research, covering East–West and traditional–modern medicine.
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