股骨近端骨折经内固定治疗后的抗凝药物治疗--以治疗时间为质量标准的并发症和死亡率。

Christoph Johannes Neumann, Tim Dario Kaiser, Rüdiger Smektala
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引用次数: 0

摘要

关于老年患者髋部骨折后的最佳手术时间,国际上一直存在争论。在延迟骨折手术治疗方面,预先存在的抗凝似乎是一个主要问题。我们的分析基于德国人口最多的联邦州--北莱茵威斯特法伦州的外部住院患者质量保证数据。我们确定了 13201 名在 2015 年 1 月至 2017 年 12 月期间接受治疗、服用抗血栓药物且年龄不低于 65 岁的髋部骨折患者。除了原有的心力衰竭外,我们无法确定某些合并症能够清楚地说明为何会出现延迟。在大多数情况下,服用抗血栓药物的患者由于严重的合并症,其预后较差。如果这些患者的手术延迟,治疗效果会更差。因此,必须避免延迟超过 24 小时的手术,以降低并发症的风险。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Anticoagulant Medication in Endoprosthetically Treated Proximal Femur Fracture - Complications and Mortality Considering the Time of Treatment as a Quality Criterion.

There is an international debate on the optimal time to surgery following hip fracture in older patients. Pre-existing anticoagulation seems to be a major concern when it comes to a delay in operative fracture treatment. The aim of this study was to examine complication and mortality rates for elderly anticoagulated hip fracture patients considering early (< 24 h) vs. delayed (> 24 h) surgery.Our Analysis is based on data of the external inpatient quality assurance of North Rhine Westphalia as the most populous German federal state. We identified 13,201 hip fracture patients with antithrombotic medication and a minimum age of 65 years treated from January 2015 to December 2017.Delayed surgery was associated with significantly higher rates of general and surgical complications as well as mortality. Except for pre-existing heart failure, we were not able to identify certain comorbidities that could clearly indicate, why there might have been a delay.In most cases, patients with antithrombotic medication have a poor outcome to be expected due to serious comorbidity. If there was a delay in surgery for those patients, treatment results were even worse. Thus, surgery with a delay of > 24 h must be avoided to reduce the risk of complications.

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