Virly Nanda Muzellina, Steven Alvianto, Nicolas Daniel Widjanarko
{"title":"利用益生菌缓解结肠镜检查后的胃肠道症状:系统回顾与元分析》。","authors":"Virly Nanda Muzellina, Steven Alvianto, Nicolas Daniel Widjanarko","doi":"10.2478/rjim-2024-0023","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Colonoscopy is regarded as a safe diagnostic and therapeutic procedure, nevertheless, some patients may still encounter post-colonoscopy gastrointestinal symptoms. This study aimed to evaluate the utilization of probiotics before and after colonoscopy to relieve those symptoms.</p><p><strong>Methodology: </strong>This study was conducted using the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) 2020 guidelines. Included studies were all interventional studies examining the effects of probiotics use before and after colonoscopy. Articles were retrieved from MEDLINE, EBSCO-Host, Cochrane, ProQuest, and Google Scholar electronic databases, utilized specific keywords <i>(</i> <i>\"</i> <i>Probiotic</i> <i>\" OR \"</i> <i>Probiotics</i> <i>\"</i>) <i>AND</i> (<i>\"</i> <i>Colonoscopy</i> <i>\" OR \"</i> <i>Colonoscopies</i> <i>\"</i>). The Cochrane Risk of Bias (RoB) 2 and Joanna Briggs Institute (JBI) Critical Appraisal tools were used for study quality assessment, as well as Review Manager (RevMan) 5.4 to perform the meta-analysis.</p><p><strong>Results: </strong>A total of ten studies were included in this systematic review. Six studies assessed the effect of probiotics consumption after colonoscopy, three examined the impact before colonoscopy, and one study assessed both. The most common type of probiotics used were <i>Lactobacillus</i> and <i>Bifidobacterium</i>. Quantitative synthesis of probiotics before colonoscopy showed no significant differences among bloating, abdominal pain, nausea, and vomiting symptoms (p=0.49, p=0.14, p=0.30, and p=0.42, respectively). Similarly, quantitative synthesis of probiotics after colonoscopy showed no significant differences in bloating and abdominal pain (p=0.16 and p=0.63, respectively).</p><p><strong>Conclusions: </strong>Probiotic administration pre- and post-colonoscopy exhibited preliminary evidence for reducing gastrointestinal symptoms, but a quantitative synthesis revealed non-significant findings, necessitating further investigations.</p>","PeriodicalId":21463,"journal":{"name":"Romanian Journal of Internal Medicine","volume":null,"pages":null},"PeriodicalIF":1.6000,"publicationDate":"2024-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Utilization of Probiotics in Relieving Post-Colonoscopy Gastrointestinal Symptoms: A Systematic Review and Meta-Analysis.\",\"authors\":\"Virly Nanda Muzellina, Steven Alvianto, Nicolas Daniel Widjanarko\",\"doi\":\"10.2478/rjim-2024-0023\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>Colonoscopy is regarded as a safe diagnostic and therapeutic procedure, nevertheless, some patients may still encounter post-colonoscopy gastrointestinal symptoms. This study aimed to evaluate the utilization of probiotics before and after colonoscopy to relieve those symptoms.</p><p><strong>Methodology: </strong>This study was conducted using the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) 2020 guidelines. Included studies were all interventional studies examining the effects of probiotics use before and after colonoscopy. Articles were retrieved from MEDLINE, EBSCO-Host, Cochrane, ProQuest, and Google Scholar electronic databases, utilized specific keywords <i>(</i> <i>\\\"</i> <i>Probiotic</i> <i>\\\" OR \\\"</i> <i>Probiotics</i> <i>\\\"</i>) <i>AND</i> (<i>\\\"</i> <i>Colonoscopy</i> <i>\\\" OR \\\"</i> <i>Colonoscopies</i> <i>\\\"</i>). The Cochrane Risk of Bias (RoB) 2 and Joanna Briggs Institute (JBI) Critical Appraisal tools were used for study quality assessment, as well as Review Manager (RevMan) 5.4 to perform the meta-analysis.</p><p><strong>Results: </strong>A total of ten studies were included in this systematic review. Six studies assessed the effect of probiotics consumption after colonoscopy, three examined the impact before colonoscopy, and one study assessed both. The most common type of probiotics used were <i>Lactobacillus</i> and <i>Bifidobacterium</i>. Quantitative synthesis of probiotics before colonoscopy showed no significant differences among bloating, abdominal pain, nausea, and vomiting symptoms (p=0.49, p=0.14, p=0.30, and p=0.42, respectively). Similarly, quantitative synthesis of probiotics after colonoscopy showed no significant differences in bloating and abdominal pain (p=0.16 and p=0.63, respectively).</p><p><strong>Conclusions: </strong>Probiotic administration pre- and post-colonoscopy exhibited preliminary evidence for reducing gastrointestinal symptoms, but a quantitative synthesis revealed non-significant findings, necessitating further investigations.</p>\",\"PeriodicalId\":21463,\"journal\":{\"name\":\"Romanian Journal of Internal Medicine\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.6000,\"publicationDate\":\"2024-06-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Romanian Journal of Internal Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2478/rjim-2024-0023\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Romanian Journal of Internal Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2478/rjim-2024-0023","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
摘要
简介:结肠镜检查被认为是一种安全的诊断和治疗方法:结肠镜检查被认为是一种安全的诊断和治疗方法,但一些患者在结肠镜检查后仍可能出现胃肠道症状。本研究旨在评估结肠镜检查前后使用益生菌缓解这些症状的情况:本研究采用《系统综述和荟萃分析首选报告项目》(Preferred Reporting Items for Systematic Reviews and Meta-Analysis, PRISMA)2020 指南进行。纳入的研究均为检查结肠镜检查前后使用益生菌效果的干预性研究。文章从 MEDLINE、EBSCO-Host、Cochrane、ProQuest 和 Google Scholar 电子数据库中检索,使用特定关键词("益生菌 "或 "益生菌")和("结肠镜检查 "或 "结肠镜检查")。使用 Cochrane Risk of Bias (RoB) 2 和 Joanna Briggs Institute (JBI) Critical Appraisal 工具进行研究质量评估,并使用 Review Manager (RevMan) 5.4 进行荟萃分析:本系统综述共纳入十项研究。其中六项研究评估了结肠镜检查后服用益生菌的效果,三项研究探讨了结肠镜检查前服用益生菌的影响,一项研究对两者都进行了评估。最常用的益生菌是乳酸杆菌和双歧杆菌。结肠镜检查前定量合成益生菌的结果显示,腹胀、腹痛、恶心和呕吐症状之间没有显著差异(分别为 p=0.49、p=0.14、p=0.30 和 p=0.42)。同样,结肠镜检查后益生菌的定量合成显示,腹胀和腹痛症状无明显差异(分别为 p=0.16 和 p=0.63):结论:在结肠镜检查前后服用益生菌可减轻胃肠道症状的初步证据,但定量综合结果显示并无显著差异,因此有必要进行进一步研究。
Utilization of Probiotics in Relieving Post-Colonoscopy Gastrointestinal Symptoms: A Systematic Review and Meta-Analysis.
Introduction: Colonoscopy is regarded as a safe diagnostic and therapeutic procedure, nevertheless, some patients may still encounter post-colonoscopy gastrointestinal symptoms. This study aimed to evaluate the utilization of probiotics before and after colonoscopy to relieve those symptoms.
Methodology: This study was conducted using the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) 2020 guidelines. Included studies were all interventional studies examining the effects of probiotics use before and after colonoscopy. Articles were retrieved from MEDLINE, EBSCO-Host, Cochrane, ProQuest, and Google Scholar electronic databases, utilized specific keywords ("Probiotic" OR "Probiotics") AND ("Colonoscopy" OR "Colonoscopies"). The Cochrane Risk of Bias (RoB) 2 and Joanna Briggs Institute (JBI) Critical Appraisal tools were used for study quality assessment, as well as Review Manager (RevMan) 5.4 to perform the meta-analysis.
Results: A total of ten studies were included in this systematic review. Six studies assessed the effect of probiotics consumption after colonoscopy, three examined the impact before colonoscopy, and one study assessed both. The most common type of probiotics used were Lactobacillus and Bifidobacterium. Quantitative synthesis of probiotics before colonoscopy showed no significant differences among bloating, abdominal pain, nausea, and vomiting symptoms (p=0.49, p=0.14, p=0.30, and p=0.42, respectively). Similarly, quantitative synthesis of probiotics after colonoscopy showed no significant differences in bloating and abdominal pain (p=0.16 and p=0.63, respectively).
Conclusions: Probiotic administration pre- and post-colonoscopy exhibited preliminary evidence for reducing gastrointestinal symptoms, but a quantitative synthesis revealed non-significant findings, necessitating further investigations.