将伽马干扰素诱导蛋白 10 Kda 和 C 反应蛋白作为自发性细菌性腹膜炎诊断标志物的研究

Afro-Egyptian Journal of Infectious and Endemic Diseases Pub Date : 2024-06-01 DOI:10.21608/aeji.2024.273972.1363

Tary Salman, Sherif Abbass, Karim Kamal, Sara Saied, Eman Abdelsameea

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引用次数: 0

摘要

而非 SBP 患者为 62.62 ± 8.76 岁。SBP 患者的腹水 CRP 和 IP-10 水平明显高于非 SBP 患者（分别为 1.45 ± 0.16 vs. 1.08 ± 0.2 mg/L; P<0.001 和 1794.33 ± 175.65 vs. 1451.06 ± 178.78 pg/ml; P<0.001）。截断值为 1.25 mg/L 时，腹水 CRP 检测 SBP 的灵敏度为 95.6%，特异度为 80.0%（曲线下面积：0.931）。截断值为 1619.3 pg/ml 的腹水 IP-10 对检测 SBP 的敏感性为 91.1%，特异性为 80.0%（曲线下面积：0.907）。两者均与腹水多形核计数和血清 CRP 相关。结论腹水中的 CRP 和 IP-10 水平似乎是诊断 SBP 的令人满意的辅助指标。

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Study use of Interferon Gamma-Induced Protein 10 Kda and C-Reactive Protein as Diagnostic Markers for Spontaneous Bacterial Peritonitis

years while in non-SBP patients was 62.62 ± 8.76 years. Ascitic fluid CRP and IP-10 levels were significantly higher in SBP patients than in non-SBP patients (1.45 ± 0.16 vs. 1.08 ± 0.2 mg/L; P<0.001 and 1794.33 ± 175.65 vs. 1451.06 ± 178.78 pg/ml; P<0.001), respectively. At a cut-off value of 1.25 mg/L, ascitic fluid CRP had a sensitivity of 95.6% and a specificity of 80.0% for detection of SBP (area under the curve: 0.931). A cut-off value of 1619.3 pg/ml, ascitic fluid IP-10 had a sensitivity of 91.1% and a specificity of 80.0% for detection of SBP (area under the curve: 0.907). Both correlated with ascitic polymorphonuclear count and serum CRP. Conclusion: Ascitic fluid levels of CRP and IP-10 seem to represent satisfactory adjunction in diagnosis of SBP.

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Afro-Egyptian Journal of Infectious and Endemic Diseases

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