干预机器人:高速灌装线干预概念验证法:摘除手套

IF 2.7 4区 医学 Q2 PHARMACOLOGY & PHARMACY
Ivo Dekker, Pieter Waelbers, Wido Tancer, Karel Kellens, Eric Demeester
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引用次数: 0

摘要

目的虽然药品高速灌装线已实现全自动化,但仍需通过手套口进行人工干预。将机器人引入高速生产线进行干预处理可提高系统的产量和无菌性。本手稿中介绍的工作提出了一种半自主干预策略,用于清除错误的柱塞。方法基于 YOLOv8 的计算机视觉算法可持续监控柱塞进给状态。自主运动规划用于大型、一般的运动,而带有系统引导的人工远程操作则用于小型、精确的运动。由 22 名志愿者组成的用户测试表明,当柱塞处于静态和动态时,未经训练的操作员可以通过该系统在平均 \(\pm 30\)s 和 \(\pm 21\)s 的时间内完成远程操作干预。通过基于李克特量表的问卷调查,测试组发现触觉系统非常直观。此外,该系统还能通过两台笔记本电脑完全远程运行,测试距离最远可达 100 公里。在静态和动态情况下,与目前基于手套的方法(2 至 3 分钟)相比,操作时间都有所缩短。该系统可以完全远程运行,用户群认为非常直观。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Robots for Interventions: Proof-of-Concept Method for High-Speed Filling Line Interventions Towards the Removal of Gloves

Robots for Interventions: Proof-of-Concept Method for High-Speed Filling Line Interventions Towards the Removal of Gloves

Purpose

Although pharmaceutical high-speed filling lines are fully automated, interventions are still performed by hand via glove ports. Bringing robots into the high-speed production lines for the handling of interventions could increase both the thoughput and the sterility of the system. The work presented in this manuscript proposes a semi-autonomous intervention strategy for the removal of erroneous plungers.

Methods

A YOLOv8-based computer vision algorithm continuously monitors the state of the plunger feed. Autonomous motion planning is used for large, general movements, while human-operated teleoperation with system guidance allows for small, precise motions. The combination of both creates a intuitive, gloveless intervention method.

Results

A user test with a group of 22 volunteers shows that an untrained operator can perform the teleoperated intervention via this system in an average of \(\pm 30\)s and \(\pm 21\)s when the plungers are static and dynamic respectively. Via a Likert-scale based questionnaire, it was found that the test group experienced the haptic system as very intuitive. Additionally, the system is capable of running completely remotely via a two-laptop setup, which has been tested at distances up to 100km.

Conclusion

An intuitive, haptic semi-autonomous teleoperation system is created for the execution of a plunger removal intervention. Both in a static and dynamic scenario, an improvement of the operating time is observed compared to the current glove-based method (2 to 3 min). The system can run fully remotely and was found to be very intuitive by the user group.

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来源期刊
Journal of Pharmaceutical Innovation
Journal of Pharmaceutical Innovation PHARMACOLOGY & PHARMACY-
CiteScore
3.70
自引率
3.80%
发文量
90
审稿时长
>12 weeks
期刊介绍: The Journal of Pharmaceutical Innovation (JPI), is an international, multidisciplinary peer-reviewed scientific journal dedicated to publishing high quality papers emphasizing innovative research and applied technologies within the pharmaceutical and biotechnology industries. JPI''s goal is to be the premier communication vehicle for the critical body of knowledge that is needed for scientific evolution and technical innovation, from R&D to market. Topics will fall under the following categories: Materials science, Product design, Process design, optimization, automation and control, Facilities; Information management, Regulatory policy and strategy, Supply chain developments , Education and professional development, Journal of Pharmaceutical Innovation publishes four issues a year.
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