磷化铝中毒后的溶血性尿毒症：病例报告

Q3 Medicine

Acta medica Iranica Pub Date : 2024-06-08 DOI:10.18502/acta.v61i10.15664

Reza Asadzadeh, Aliashraf Mozafari, F. Taghinezhad, Fatemeh Pourrezagholi, Zahra Khalighi

{"title":"磷化铝中毒后的溶血性尿毒症：病例报告","authors":"Reza Asadzadeh, Aliashraf Mozafari, F. Taghinezhad, Fatemeh Pourrezagholi, Zahra Khalighi","doi":"10.18502/acta.v61i10.15664","DOIUrl":null,"url":null,"abstract":"Aluminum Phosphide (ALP) is an effective, cheap, and highly toxic pesticide. ALP poisoning can have destructive effects on the human body, such as the heart, lungs, gastrointestinal tract, kidneys, and central nervous system, although all organs can be involved. We describe a 53-year-old Iranian Kurdish man with Hemolytic Uremic Syndrome (HUS) and Acute Kidney Injury (AKI). Supportive treatments such as hemodialysis and plasmapheresis were performed. After 23 days of hospitalization, the patient fully recovered and was discharged. Thrombotic microangiopathy such as HUS should be considered in patients with ALP toxicity that has a genetic defect in complement proteins. Combined use of hemodialysis and plasmapheresis improve outcomes in these patients.","PeriodicalId":6946,"journal":{"name":"Acta medica Iranica","volume":" 22","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Hemolytic Uremic Syndrome Following the Aluminum Phosphide Poisoning: A Case Report\",\"authors\":\"Reza Asadzadeh, Aliashraf Mozafari, F. Taghinezhad, Fatemeh Pourrezagholi, Zahra Khalighi\",\"doi\":\"10.18502/acta.v61i10.15664\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Aluminum Phosphide (ALP) is an effective, cheap, and highly toxic pesticide. ALP poisoning can have destructive effects on the human body, such as the heart, lungs, gastrointestinal tract, kidneys, and central nervous system, although all organs can be involved. We describe a 53-year-old Iranian Kurdish man with Hemolytic Uremic Syndrome (HUS) and Acute Kidney Injury (AKI). Supportive treatments such as hemodialysis and plasmapheresis were performed. After 23 days of hospitalization, the patient fully recovered and was discharged. Thrombotic microangiopathy such as HUS should be considered in patients with ALP toxicity that has a genetic defect in complement proteins. Combined use of hemodialysis and plasmapheresis improve outcomes in these patients.\",\"PeriodicalId\":6946,\"journal\":{\"name\":\"Acta medica Iranica\",\"volume\":\" 22\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-06-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Acta medica Iranica\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.18502/acta.v61i10.15664\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta medica Iranica","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.18502/acta.v61i10.15664","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}

引用次数: 0

摘要

磷化铝（ALP）是一种高效、廉价、剧毒的杀虫剂。ALP 中毒会对人体造成破坏性影响，如心脏、肺部、胃肠道、肾脏和中枢神经系统，尽管所有器官都可能受累。我们描述了一名 53 岁的伊朗库尔德男子，他患有溶血性尿毒症（HUS）和急性肾损伤（AKI）。患者接受了血液透析和血浆置换等支持性治疗。住院 23 天后，患者完全康复出院。对于存在补体蛋白遗传缺陷的 ALP 中毒患者，应考虑血栓性微血管病，如 HUS。联合使用血液透析和血浆置换可改善这些患者的预后。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Hemolytic Uremic Syndrome Following the Aluminum Phosphide Poisoning: A Case Report

Aluminum Phosphide (ALP) is an effective, cheap, and highly toxic pesticide. ALP poisoning can have destructive effects on the human body, such as the heart, lungs, gastrointestinal tract, kidneys, and central nervous system, although all organs can be involved. We describe a 53-year-old Iranian Kurdish man with Hemolytic Uremic Syndrome (HUS) and Acute Kidney Injury (AKI). Supportive treatments such as hemodialysis and plasmapheresis were performed. After 23 days of hospitalization, the patient fully recovered and was discharged. Thrombotic microangiopathy such as HUS should be considered in patients with ALP toxicity that has a genetic defect in complement proteins. Combined use of hemodialysis and plasmapheresis improve outcomes in these patients.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Acta medica Iranica Medicine-Medicine (all)

CiteScore

0.70

自引率

0.00%

发文量

审稿时长

18 weeks

期刊介绍： ACTA MEDICA IRANICA (p. ISSN 0044-6025; e. ISSN: 1735-9694) is the official journal of the Faculty of Medicine, Tehran University of Medical Sciences. The journal is the oldest scientific medical journal of the country, which has been published from 1960 onward in English language. Although it had been published quarterly in the past, the journal has been published bimonthly (6 issues per year) from the year 2004. Acta Medica Iranica it is an international journal with multidisciplinary scope which publishes original research papers, review articles, case reports, and letters to the editor from all over the world. The journal has a wide scope and allows scientists, clinicians, and academic members to publish their original works in this field.