Evaluation of Global and Regional Strain and Angiographic Correlation in Patients with Non-ST Elevation Acute Coronary Syndrome (NSTE-ACS)

Non ST elevated acute coronary syndrome (NSTE-ACS) is common and comprises of around one third of total patient of acute coronary syndrome (ACS). Evaluation and management is difficult due to complex pathophysiology involved. Traditionally echocardiography helps to assess these patients non-invasively before they are taken to cardiac catheterization laboratory. Speckle tracking echocardiography (STE) is an evolving modality by which more accurate assessment of left ventricular (LV) function can be done. STE also helps in identification of culprit artery responsible for the cardiac event. In our study we tried to correlate angiographic finding with global and regional strain echocardiography of LV in patients with NSTE-ACS. Total 50 patients were included in this cross- sectional study and we found that poor global longitudinal strain (GLS) of LV was associated with critical, multivessel coronary artery disease (MVCAD) with or without involvement of Left main coronary artery (LMCA) Key words: NSTE-ACS, LV, Regional strain, global strain, STE