3种免疫酶试剂盒检测抗lav抗体的评价。与确认测试的比较。国家输血协会研究小组]。

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引用次数: 0

摘要

对三种检测抗lav /HTLV III抗体的酶免疫检测试剂盒进行了评价:Diagnostics Pasteur (Elavia) Abbott Laboratories (Abbott/HTLV III)和Organon (Vironostika)。共对6017名献血者(5980名未入选者和37名囚犯)和55名血清阴性或血清阳性样本进行了测试。这3种试剂盒之间的差异非常微弱:abbot - htlv III似乎是最不特异性和最敏感的,而Vironostika是最特异性和最不敏感的。给出了ELISA的定量结果,并与间接免疫荧光、Western-Blot和放射免疫沉淀的结果进行了比较。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Evaluation of 3 immuno-enzyme kits for the detection of anti-LAV antibodies. Comparison with confirmation tests. Study Subgroup of the National Blood Transfusion Society].

Three enzymo immuno assay kits for the detection of anti-LAV/HTLV III antibodies were evaluated: Diagnostics Pasteur (Elavia) Abbott Laboratories (Abbott/HTLV III) and Organon (Vironostika). A total of 6017 blood donors (5980 unselected and 37 prisoners) and a panel of 55 sero negative or sero positive samples were tested. Very weak differences were noted between these 3 kits: Abbott-HTLV III seems the least specific and the most sensitive and Vironostika the most specific and the least sensitive. ELISA quantitative results are given and compared to the results obtained by indirect immunofluorescence, Western-Blot and radio immuno precipitation.

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