甲型流感感染者的颅内高压:意外诊断

Jolsana Augustine, Caroline Theresa Paulson, Khadiga Abdalla, Ahmed Ahmed Ebied, Mohammed Harriss
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摘要

摘要 特发性颅内高压症(ICH)是一种神经系统综合征,由无特定病因的颅内压升高决定。这种疾病的确切病理生理学尚不清楚。视黄醇、类固醇激素的摄入、高体重指数、细胞因子的释放和脂肪因子水平都可能是诱因或相关因素。在成人中很少观察到流感与 ICH 的关联。临床症状可能是头痛、视力障碍、复视和耳鸣,由于这些症状相互重叠,在急性流感发作时很容易被漏诊。尽管乳头水肿被认为是最特异的体征,但却很少被发现。磁共振成像上的神经放射学征象可能提示特发性 ICH 的诊断。必须进行眼科评估,以发现视力丧失形式的并发症和后遗症。腰椎穿刺和脑脊液开口压力测量有助于确诊和缓解压力,也是治疗的一部分。根据美国疾病控制中心发布的信息,流感是一种可预防的疾病,每年都要接种针对当年和该地区特定病毒株的疫苗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Intracranial Hypertension in a Person Infected with Influenza A: An Accidental Diagnosis
ABSTRACT Idiopathic intracranial hypertension (ICH) is a neurological syndrome determined by a rise in intracranial pressure without a specific cause. The exact pathophysiology of this disease is unknown. Intake of retinoids, steroid hormones, high body mass index, release of cytokines, and adipokine levels could be possible causal or associated factors. The association of influenza with ICH has been observed rarely in adults. The clinical symptoms can be headache, disturbance of vision, diplopia, and tinnitus, which can be very well missed during an acute flu attack as the symptoms overlap. Even though papilledema is considered the most specific sign, it is rarely found. Neuroradiological signs on magnetic resonance imaging may suggest the diagnosis of idiopathic ICH. Ophthalmological evaluation is mandatory to find out complications and sequelae in the form of visual loss. Lumbar puncture and cerebrospinal fluid opening pressure measurement are helpful in establishing a diagnosis as well as relieving pressures as part of the management. Influenza is a preventable disease with the administration of a yearly vaccine against specific strains of the virus for the year and region, as released by the Center for Disease Control.
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