Rh(III)催化的苯甲酰胺氧化还原中性 C-H 多氟烯化反应

Synthesis Pub Date : 2024-06-11 DOI:10.1055/a-2343-0676
Jia-Qiang Wu, Wei Lin, Yifei Qu, Mei Xie, Huixuan Zhu, Jinhui Hu, Zhuang Xiong, Jun Xu, Wenhua Chen
{"title":"Rh(III)催化的苯甲酰胺氧化还原中性 C-H 多氟烯化反应","authors":"Jia-Qiang Wu, Wei Lin, Yifei Qu, Mei Xie, Huixuan Zhu, Jinhui Hu, Zhuang Xiong, Jun Xu, Wenhua Chen","doi":"10.1055/a-2343-0676","DOIUrl":null,"url":null,"abstract":"Fluorinated molecules are widely used in pharmaceutical and agrochemical industries. Multifluoroalkyl-containing compounds have attracted increasing attention for their unique ability to alter the activity of drugs and bioactive molecules. Herein, we report an efficient Rh(III)-catalyzed redox-neutral C-H multifluoroalkenylation of benzamides with multifluoroalkenes, which provides a versatile protocol for accessing a wide range of multifluoroalkenylated arenes.","PeriodicalId":501298,"journal":{"name":"Synthesis","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Rh(III)-Catalyzed Redox-neutral C-H Multifluoroalkenylation of Benzamides\",\"authors\":\"Jia-Qiang Wu, Wei Lin, Yifei Qu, Mei Xie, Huixuan Zhu, Jinhui Hu, Zhuang Xiong, Jun Xu, Wenhua Chen\",\"doi\":\"10.1055/a-2343-0676\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Fluorinated molecules are widely used in pharmaceutical and agrochemical industries. Multifluoroalkyl-containing compounds have attracted increasing attention for their unique ability to alter the activity of drugs and bioactive molecules. Herein, we report an efficient Rh(III)-catalyzed redox-neutral C-H multifluoroalkenylation of benzamides with multifluoroalkenes, which provides a versatile protocol for accessing a wide range of multifluoroalkenylated arenes.\",\"PeriodicalId\":501298,\"journal\":{\"name\":\"Synthesis\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-06-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Synthesis\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1055/a-2343-0676\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Synthesis","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1055/a-2343-0676","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

氟化分子广泛应用于制药和农用化学品行业。含多氟烷基的化合物因其改变药物和生物活性分子活性的独特能力而受到越来越多的关注。在此,我们报告了一种高效的 Rh(III) 催化的多氟烯烃与苯甲酰胺的氧化还原中性 C-H 多氟烯烃化反应,该反应为获得多种多氟烯烃化的炔类化合物提供了一种多功能方案。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Rh(III)-Catalyzed Redox-neutral C-H Multifluoroalkenylation of Benzamides

Rh(III)-Catalyzed Redox-neutral C-H Multifluoroalkenylation of Benzamides
Fluorinated molecules are widely used in pharmaceutical and agrochemical industries. Multifluoroalkyl-containing compounds have attracted increasing attention for their unique ability to alter the activity of drugs and bioactive molecules. Herein, we report an efficient Rh(III)-catalyzed redox-neutral C-H multifluoroalkenylation of benzamides with multifluoroalkenes, which provides a versatile protocol for accessing a wide range of multifluoroalkenylated arenes.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信