美国西南部三个地区的沙尘暴与心肺急诊室就诊情况:基于监测的暴露量度的应用

Claire Rowan, R. D'souza, Xiaping Zheng, James L Crooks, Kirk Hohsfield, Daniel Q Tong, Howard H. Chang, S. Ebelt
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摘要

背景:预计气候变化将增加沙尘暴的风险,尤其是在亚热带干旱地区,包括美国西南部。在美国,有关沙尘暴对健康影响的研究十分有限,并且受到沙尘暴识别难题的阻碍。本研究评估了美国西南部沙尘暴与心肺急诊室就诊之间的潜在联系。方法:我们从亚利桑那州、加利福尼亚州和犹他州的 8 个 IMPROVE(受保护视觉环境机构间监测)站点获取了 2005-2016 年的数据。我们采用一种经过验证的算法来识别每个站点的沙尘暴日。我们从州立机构获取了患者级别的急诊就诊数据,并确定了居住在 IMPROVE 站点 50 公里范围内邮政编码的患者中呼吸系统、心血管和特定病因亚组的就诊情况。通过病例交叉设计,我们估算了急诊室就诊与沙尘暴的短期关联,并控制了随时间变化的协变量。结果显示2005-2016 年间,8 个 IMPROVE 站点共出现了 40 个沙尘暴日。沙尘暴日的 PM10 和 PM2.5 平均水平是非沙尘暴日的 3-6 倍。在研究期间,共有 2,524,259 人次到呼吸科就诊,2,805,925 人次到心血管科就诊。在沙尘暴后 1、2 和 3 天的滞后期,我们观察到与非沙尘暴日相比,呼吸道急诊就诊率分别上升了 3.7%(95% CI:1.0%,7.6%)、4.9%(95% CI:1.1%,8.9%)和 5.0%(95% CI:1.3%,8.9%)。沙尘暴日与心血管疾病急诊就诊率的估计相关性与空值基本一致。结论:利用基于监测的暴露指标,我们观察到沙尘暴与呼吸道急诊就诊之间存在关联。这些结果进一步证明了沙尘暴对健康的威胁。沙尘暴指标因缺乏每日数据而受到限制;未来的研究应考虑卫星和数值模型提供的信息,以加强沙尘暴的特征描述。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Dust storms and cardiorespiratory emergency department visits in three southwestern United States: application of a monitoring-based exposure metric
Background: Climate change is projected to increase the risk of dust storms, particularly in subtropical dryland, including the southwestern US. Research on dust storm’s health impacts in the US is limited and hindered by challenges in dust storm identification. This study assesses the potential link between dust storms and cardiorespiratory emergency department (ED) visits in the southwestern US. Methods: We acquired data for 2005-2016 from 8 IMPROVE (Interagency Monitoring of PROtected Visual Environments) sites in Arizona, California, and Utah. We applied a validated algorithm to identify dust storm days at each site. We acquired patient-level ED visit data from state agencies and ascertained visits for respiratory, cardiovascular, and cause-specific subgroups among patients residing in ZIP codes within 50 km of an IMPROVE site. Using a case-crossover design, we estimated short-term associations of ED visits and dust storms, controlling for temporally varying covariates. Results: During 2005-2016, 40 dust storm days occurred at the 8 IMPROVE sites. Mean PM10 and PM2.5 levels were 3-6 times greater on dust storm days compared to non-dust storm days. Over the study period, there were 2,524,259 respiratory and 2,805,925 cardiovascular ED visits. At lags of 1, 2, and 3 days after a dust storm, we observed 3.7% (95% CI: 1.0%, 7.6%), 4.9% (95% CI: 1.1%, 8.9%), and 5.0% (95% CI: 1.3%, 8.9%) elevated odds of respiratory ED visits compared to non-dust storm days. Estimated associations of dust storm days and cardiovascular disease ED visits were largely consistent with the null. Conclusions: Using a monitoring-based exposure metric, we observed associations among dust storms and respiratory ED visits. The results add to growing evidence of the health threat posed by dust storms. The dust storm metric was limited by lack of daily data; future research should consider information from satellite and numerical models to enhance dust storm characterization.
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