1-Thiosugars：从合成到应用

IF 1.7 3区化学 Q3 CHEMISTRY, ORGANIC

Current Organic Chemistry Pub Date : 2024-06-14 DOI:10.2174/0113852728314452240524112438

Surabhi Gupta, Charles Gauthier

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引用次数: 0

摘要

1 硫代糖及其糖苷在碳水化合物化学中发挥着至关重要的作用，这主要是由于它们具有模仿 O 型糖苷的易用性和潜力。硫代糖苷的合成方法一直是个难题。近年来，研究人员对探索硫代糖苷在各个领域的应用表现出越来越浓厚的兴趣，包括开发天然产物衍生物、寡糖和多糖仿生、金属药物和树枝状聚合物。硫代糖合成的方法和方案层出不穷。本综述旨在全面介绍硫代糖的制备及其作为合成前体的应用。

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1-Thiosugars: From Synthesis to Applications

1-Thiosugars and their glycosides play crucial roles in carbohydrate chemistry, primarily due to their stability and potential for mimicking O-glycosides. The synthetic methodologies for thioglycosides pose ongoing challenges. In recent years, researchers have shown a growing interest in exploring the applications of thiosugars in various fields, including the development of natural product derivatives, oligo- and polysaccharide mimics, metallodrugs, and dendrimers. Numerous approaches and protocols have been devised for the synthesis of thiosugars. This review aims to comprehensively cover the efforts towards preparing thiosugars and their application as synthetic precursors.

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来源期刊

Current Organic Chemistry 化学-有机化学

CiteScore

3.70

自引率

7.70%

发文量

审稿时长

1 months

期刊介绍： Current Organic Chemistry aims to provide in-depth/mini reviews on the current progress in various fields related to organic chemistry including bioorganic chemistry, organo-metallic chemistry, asymmetric synthesis, heterocyclic chemistry, natural product chemistry, catalytic and green chemistry, suitable aspects of medicinal chemistry and polymer chemistry, as well as analytical methods in organic chemistry. The frontier reviews provide the current state of knowledge in these fields and are written by chosen experts who are internationally known for their eminent research contributions. The Journal also accepts high quality research papers focusing on hot topics, highlights and letters besides thematic issues in these fields. Current Organic Chemistry should prove to be of great interest to organic chemists in academia and industry, who wish to keep abreast with recent developments in key fields of organic chemistry.