{"title":"研究轻微缺血性脑卒中或短暂性脑缺血发作患者的临床特征、心理健康和血管功能之间的关系。","authors":"Witid Mitranun, Witoon Mitarnun, Prasit Peepathum, Amorntheap Wandee, Wenika Mitarnun, Wilasinee Pangwong, Tanormsak Senakham","doi":"10.52965/001c.118443","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Over the past decade, there has been extensive research exploring the relationship between vascular health and mental well-being, encompassing aspects such as mood and cognition. However, there is a notable gap in research focusing on the mental and vascular conditions of minor ischemic stroke or transient ischemic attack (TIA) patients, particularly within the Thai population.</p><p><strong>Objectives: </strong>To investigate the clinical characteristics and mental issues related to vascular functions in patients who have experienced a minor ischemic stroke or TIA. This study, approved by the Buriram Hospital Ethics Committee (IRB: BR0033.102.1/8), adhered to the guidelines of the Helsinki Declaration and obtained informed consent from all participants.</p><p><strong>Methods: </strong>A prospective cross-sectional study was conducted at Buriram Hospital, a government regional hospital located in Buriram province, Thailand, involving twenty-three participants diagnosed with minor ischemic stroke or TIA. Measurements included clinical characteristics, Hospital Anxiety and Depression Scale-part Anxiety (HADS-A), Hospital Anxiety and Depression Scale-part Depression (HADS-D), mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), flow-mediated dilation (FMD), and brachial-ankle pulse wave velocity (baPWV). Linear regression analysis was employed to investigate the factors associated with vascular function (FMD and baPWV).</p><p><strong>Results: </strong>The factor related to FMD was HADS-D (β = -0.5, 95% CI -0.33 to -0.04). Factors associated with baPWV included age (β = 0.51, 95% CI 5.05 to 39.50) and the duration of minor ischemic stroke or TIA (β = 0.48, 95% CI 25.41 to 290.99).</p><p><strong>Conclusions: </strong>FMD shows a connection with depressive symptoms in patients with minor ischemic stroke or TIA. Therefore, it is important to detect and provide appropriate treatment for depressive symptoms in these patients, as it may lead to improvements in vascular function and better cerebrovascular outcomes.</p>","PeriodicalId":51865,"journal":{"name":"Health Psychology Research","volume":"12 ","pages":"118443"},"PeriodicalIF":2.0000,"publicationDate":"2024-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11176051/pdf/","citationCount":"0","resultStr":"{\"title\":\"Investigating the Relationship Between Clinical Characteristics, Mental Health, and Vascular Function in Minor Ischemic Stroke or Transient Ischemic Attack Patients.\",\"authors\":\"Witid Mitranun, Witoon Mitarnun, Prasit Peepathum, Amorntheap Wandee, Wenika Mitarnun, Wilasinee Pangwong, Tanormsak Senakham\",\"doi\":\"10.52965/001c.118443\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Over the past decade, there has been extensive research exploring the relationship between vascular health and mental well-being, encompassing aspects such as mood and cognition. However, there is a notable gap in research focusing on the mental and vascular conditions of minor ischemic stroke or transient ischemic attack (TIA) patients, particularly within the Thai population.</p><p><strong>Objectives: </strong>To investigate the clinical characteristics and mental issues related to vascular functions in patients who have experienced a minor ischemic stroke or TIA. This study, approved by the Buriram Hospital Ethics Committee (IRB: BR0033.102.1/8), adhered to the guidelines of the Helsinki Declaration and obtained informed consent from all participants.</p><p><strong>Methods: </strong>A prospective cross-sectional study was conducted at Buriram Hospital, a government regional hospital located in Buriram province, Thailand, involving twenty-three participants diagnosed with minor ischemic stroke or TIA. Measurements included clinical characteristics, Hospital Anxiety and Depression Scale-part Anxiety (HADS-A), Hospital Anxiety and Depression Scale-part Depression (HADS-D), mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), flow-mediated dilation (FMD), and brachial-ankle pulse wave velocity (baPWV). Linear regression analysis was employed to investigate the factors associated with vascular function (FMD and baPWV).</p><p><strong>Results: </strong>The factor related to FMD was HADS-D (β = -0.5, 95% CI -0.33 to -0.04). Factors associated with baPWV included age (β = 0.51, 95% CI 5.05 to 39.50) and the duration of minor ischemic stroke or TIA (β = 0.48, 95% CI 25.41 to 290.99).</p><p><strong>Conclusions: </strong>FMD shows a connection with depressive symptoms in patients with minor ischemic stroke or TIA. Therefore, it is important to detect and provide appropriate treatment for depressive symptoms in these patients, as it may lead to improvements in vascular function and better cerebrovascular outcomes.</p>\",\"PeriodicalId\":51865,\"journal\":{\"name\":\"Health Psychology Research\",\"volume\":\"12 \",\"pages\":\"118443\"},\"PeriodicalIF\":2.0000,\"publicationDate\":\"2024-06-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11176051/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Health Psychology Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.52965/001c.118443\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"PSYCHOLOGY, CLINICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Health Psychology Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.52965/001c.118443","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"PSYCHOLOGY, CLINICAL","Score":null,"Total":0}
引用次数: 0
摘要
背景：在过去的十年中，人们对血管健康与心理健康之间的关系（包括情绪和认知等方面）进行了广泛的研究。然而，关于轻微缺血性中风或短暂性脑缺血发作（TIA）患者的精神和血管状况的研究却明显不足，尤其是在泰国人群中：调查轻微缺血性中风或短暂性脑缺血发作患者的临床特征以及与血管功能相关的精神问题。本研究获得了武里南医院伦理委员会（IRB：BR0033.102.1/8）的批准，遵守了《赫尔辛基宣言》的指导方针，并获得了所有参与者的知情同意：这项前瞻性横断面研究在位于泰国武里南府的政府地区医院武里南医院进行，共有 23 名被诊断为轻微缺血性中风或 TIA 的患者参与。测量项目包括临床特征、医院焦虑和抑郁量表-焦虑部分（HADS-A）、医院焦虑和抑郁量表-抑郁部分（HADS-D）、迷你精神状态检查（MMSE）、蒙特利尔认知评估（MoCA）、血流介导扩张（FMD）和肱踝脉搏波速度（baPWV）。采用线性回归分析研究了与血管功能（FMD 和 baPWV）相关的因素：结果：与 FMD 相关的因素是 HADS-D（β = -0.5，95% CI -0.33 至 -0.04）。与 baPWV 相关的因素包括年龄（β = 0.51，95% CI 5.05 至 39.50）和轻微缺血性卒中或 TIA 持续时间（β = 0.48，95% CI 25.41 至 290.99）：结论：FMD 与轻微缺血性卒中或 TIA 患者的抑郁症状有关。结论：FMD 与轻微缺血性卒中或 TIA 患者的抑郁症状有关。因此，发现这些患者的抑郁症状并对其进行适当治疗非常重要，因为这可能会改善血管功能并改善脑血管预后。
Investigating the Relationship Between Clinical Characteristics, Mental Health, and Vascular Function in Minor Ischemic Stroke or Transient Ischemic Attack Patients.
Background: Over the past decade, there has been extensive research exploring the relationship between vascular health and mental well-being, encompassing aspects such as mood and cognition. However, there is a notable gap in research focusing on the mental and vascular conditions of minor ischemic stroke or transient ischemic attack (TIA) patients, particularly within the Thai population.
Objectives: To investigate the clinical characteristics and mental issues related to vascular functions in patients who have experienced a minor ischemic stroke or TIA. This study, approved by the Buriram Hospital Ethics Committee (IRB: BR0033.102.1/8), adhered to the guidelines of the Helsinki Declaration and obtained informed consent from all participants.
Methods: A prospective cross-sectional study was conducted at Buriram Hospital, a government regional hospital located in Buriram province, Thailand, involving twenty-three participants diagnosed with minor ischemic stroke or TIA. Measurements included clinical characteristics, Hospital Anxiety and Depression Scale-part Anxiety (HADS-A), Hospital Anxiety and Depression Scale-part Depression (HADS-D), mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), flow-mediated dilation (FMD), and brachial-ankle pulse wave velocity (baPWV). Linear regression analysis was employed to investigate the factors associated with vascular function (FMD and baPWV).
Results: The factor related to FMD was HADS-D (β = -0.5, 95% CI -0.33 to -0.04). Factors associated with baPWV included age (β = 0.51, 95% CI 5.05 to 39.50) and the duration of minor ischemic stroke or TIA (β = 0.48, 95% CI 25.41 to 290.99).
Conclusions: FMD shows a connection with depressive symptoms in patients with minor ischemic stroke or TIA. Therefore, it is important to detect and provide appropriate treatment for depressive symptoms in these patients, as it may lead to improvements in vascular function and better cerebrovascular outcomes.
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