没有一种完美的 MASH 小鼠模型

IF 18.9 1区医学 Q1 ENDOCRINOLOGY & METABOLISM

Nature metabolism Pub Date : 2024-06-12 DOI:10.1038/s42255-024-01052-5

Russell P. Goodman

引用次数: 0

摘要

对近 40 种不同的 MASH 小鼠模型进行集中的代谢、组织学和转录组学评估，为选择常见肝病的相关临床前小鼠模型提供了重要资源。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

No single perfect mouse model of MASH

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No single perfect mouse model of MASH

A centralized metabolic, histologic and transcriptomic evaluation of nearly 40 different murine models of MASH provides a crucial resource for choosing relevant preclinical mouse models for a common liver disease.

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来源期刊

Nature metabolism ENDOCRINOLOGY & METABOLISM-

CiteScore

27.50

自引率

2.40%

发文量

170

期刊介绍： Nature Metabolism is a peer-reviewed scientific journal that covers a broad range of topics in metabolism research. It aims to advance the understanding of metabolic and homeostatic processes at a cellular and physiological level. The journal publishes research from various fields, including fundamental cell biology, basic biomedical and translational research, and integrative physiology. It focuses on how cellular metabolism affects cellular function, the physiology and homeostasis of organs and tissues, and the regulation of organismal energy homeostasis. It also investigates the molecular pathophysiology of metabolic diseases such as diabetes and obesity, as well as their treatment. Nature Metabolism follows the standards of other Nature-branded journals, with a dedicated team of professional editors, rigorous peer-review process, high standards of copy-editing and production, swift publication, and editorial independence. The journal has a high impact factor, has a certain influence in the international area, and is deeply concerned and cited by the majority of scholars.