Eulogio Pleguezuelos, Amin Del Carmen, Mateu Serra, Eva Moreno, Marc Miravitlles, Manuel Vicente Garnacho-Castaño
{"title":"COVID-19患者的住院时间和重症监护室停留时间与体重指数有关，会影响心肺功能。","authors":"Eulogio Pleguezuelos, Amin Del Carmen, Mateu Serra, Eva Moreno, Marc Miravitlles, Manuel Vicente Garnacho-Castaño","doi":"10.1177/14799731241259749","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>The effects of coronavirus disease 2019 (COVID-19) on the cardiorespiratory fitness of hospitalized and obese patients are of utmost relevance. This study aimed to analyze how hospital and intensive care unit (ICU) stay together with body mass index affect cardiorespiratory fitness in patients with COVID-19.</p><p><strong>Methods: </strong>251 participants (males, <i>n</i> = 118; females, <i>n</i> = 133) were assigned to four groups: non-hospitalized COVID-19 patients (<i>n</i> = 65, age: 45.3 years), hospitalized COVID-19 patients (<i>n</i> = 63, age: 57.6 years), COVID-19 patients admitted to the ICU (<i>n</i> = 61, age: 56.9 years), and control group (<i>n</i> = 62, age: 49.8 years). An incremental cardiopulmonary exercise test was performed between 3 and 6 weeks after medical discharge from hospital.</p><p><strong>Results: </strong>Higher peak oxygen uptake (VO<sub>2peak</sub>), ventilatory efficiency and power output were found in ICU patients with normal weight (NW) than in overweight (OW) (Mean difference: 0.1 L·min<sup>-1</sup>, -5.5, 29.0 W, respectively) and obese (OB) ICU patients (Mean difference: 0.1 L·min<sup>-1</sup>, -5.0, 26.2 W, respectively) (<i>p</i> < .05). In NW, OW and OB participants, higher VO<sub>2peak</sub> and power output were observed in control group compared with non-hospitalized (Mean difference: NW: 0.2 L·min<sup>-1</sup>, 83.3 W; OW: 0.2 L·min<sup>-1</sup>, 60.0 W; OB: 0.2 L·min<sup>-1</sup>, 70.9 W, respectively), hospitalized (Mean difference: NW: 0.2 L·min<sup>-1</sup>, 72.9 W; OW: 0.1 L·min<sup>-1</sup>, 58.3 W; OB: 0.2 L•min<sup>-1</sup>, 91.1 W, respectively) and ICU patients (Mean difference: NW: 0.1 L·min<sup>-1</sup>, 70.9 W; OW: 0.2 L·min<sup>-1</sup>, 91.1 W; OB: 0.3 L·min<sup>-1</sup>; 65.0 W, respectively) (<i>p</i> < .05).</p><p><strong>Conclusions: </strong>The degree of severity of COVID-19, especially identified by hospitalization and ICU stay, together with obesity and overweight were key factors in reducing cardiorespiratory fitness in patients with COVID-19.</p>","PeriodicalId":10217,"journal":{"name":"Chronic Respiratory Disease","volume":"21 ","pages":"14799731241259749"},"PeriodicalIF":3.5000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11177731/pdf/","citationCount":"0","resultStr":"{\"title\":\"Hospital and intensive care unit stay associated with body mass index affect cardiorespiratory fitness in patients with COVID-19.\",\"authors\":\"Eulogio Pleguezuelos, Amin Del Carmen, Mateu Serra, Eva Moreno, Marc Miravitlles, Manuel Vicente Garnacho-Castaño\",\"doi\":\"10.1177/14799731241259749\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>The effects of coronavirus disease 2019 (COVID-19) on the cardiorespiratory fitness of hospitalized and obese patients are of utmost relevance. This study aimed to analyze how hospital and intensive care unit (ICU) stay together with body mass index affect cardiorespiratory fitness in patients with COVID-19.</p><p><strong>Methods: </strong>251 participants (males, <i>n</i> = 118; females, <i>n</i> = 133) were assigned to four groups: non-hospitalized COVID-19 patients (<i>n</i> = 65, age: 45.3 years), hospitalized COVID-19 patients (<i>n</i> = 63, age: 57.6 years), COVID-19 patients admitted to the ICU (<i>n</i> = 61, age: 56.9 years), and control group (<i>n</i> = 62, age: 49.8 years). An incremental cardiopulmonary exercise test was performed between 3 and 6 weeks after medical discharge from hospital.</p><p><strong>Results: </strong>Higher peak oxygen uptake (VO<sub>2peak</sub>), ventilatory efficiency and power output were found in ICU patients with normal weight (NW) than in overweight (OW) (Mean difference: 0.1 L·min<sup>-1</sup>, -5.5, 29.0 W, respectively) and obese (OB) ICU patients (Mean difference: 0.1 L·min<sup>-1</sup>, -5.0, 26.2 W, respectively) (<i>p</i> < .05). In NW, OW and OB participants, higher VO<sub>2peak</sub> and power output were observed in control group compared with non-hospitalized (Mean difference: NW: 0.2 L·min<sup>-1</sup>, 83.3 W; OW: 0.2 L·min<sup>-1</sup>, 60.0 W; OB: 0.2 L·min<sup>-1</sup>, 70.9 W, respectively), hospitalized (Mean difference: NW: 0.2 L·min<sup>-1</sup>, 72.9 W; OW: 0.1 L·min<sup>-1</sup>, 58.3 W; OB: 0.2 L•min<sup>-1</sup>, 91.1 W, respectively) and ICU patients (Mean difference: NW: 0.1 L·min<sup>-1</sup>, 70.9 W; OW: 0.2 L·min<sup>-1</sup>, 91.1 W; OB: 0.3 L·min<sup>-1</sup>; 65.0 W, respectively) (<i>p</i> < .05).</p><p><strong>Conclusions: </strong>The degree of severity of COVID-19, especially identified by hospitalization and ICU stay, together with obesity and overweight were key factors in reducing cardiorespiratory fitness in patients with COVID-19.</p>\",\"PeriodicalId\":10217,\"journal\":{\"name\":\"Chronic Respiratory Disease\",\"volume\":\"21 \",\"pages\":\"14799731241259749\"},\"PeriodicalIF\":3.5000,\"publicationDate\":\"2024-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11177731/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Chronic Respiratory Disease\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1177/14799731241259749\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"RESPIRATORY SYSTEM\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chronic Respiratory Disease","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1177/14799731241259749","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"RESPIRATORY SYSTEM","Score":null,"Total":0}
Hospital and intensive care unit stay associated with body mass index affect cardiorespiratory fitness in patients with COVID-19.
Background: The effects of coronavirus disease 2019 (COVID-19) on the cardiorespiratory fitness of hospitalized and obese patients are of utmost relevance. This study aimed to analyze how hospital and intensive care unit (ICU) stay together with body mass index affect cardiorespiratory fitness in patients with COVID-19.
Methods: 251 participants (males, n = 118; females, n = 133) were assigned to four groups: non-hospitalized COVID-19 patients (n = 65, age: 45.3 years), hospitalized COVID-19 patients (n = 63, age: 57.6 years), COVID-19 patients admitted to the ICU (n = 61, age: 56.9 years), and control group (n = 62, age: 49.8 years). An incremental cardiopulmonary exercise test was performed between 3 and 6 weeks after medical discharge from hospital.
Results: Higher peak oxygen uptake (VO2peak), ventilatory efficiency and power output were found in ICU patients with normal weight (NW) than in overweight (OW) (Mean difference: 0.1 L·min-1, -5.5, 29.0 W, respectively) and obese (OB) ICU patients (Mean difference: 0.1 L·min-1, -5.0, 26.2 W, respectively) (p < .05). In NW, OW and OB participants, higher VO2peak and power output were observed in control group compared with non-hospitalized (Mean difference: NW: 0.2 L·min-1, 83.3 W; OW: 0.2 L·min-1, 60.0 W; OB: 0.2 L·min-1, 70.9 W, respectively), hospitalized (Mean difference: NW: 0.2 L·min-1, 72.9 W; OW: 0.1 L·min-1, 58.3 W; OB: 0.2 L•min-1, 91.1 W, respectively) and ICU patients (Mean difference: NW: 0.1 L·min-1, 70.9 W; OW: 0.2 L·min-1, 91.1 W; OB: 0.3 L·min-1; 65.0 W, respectively) (p < .05).
Conclusions: The degree of severity of COVID-19, especially identified by hospitalization and ICU stay, together with obesity and overweight were key factors in reducing cardiorespiratory fitness in patients with COVID-19.
期刊介绍：
Chronic Respiratory Disease is a peer-reviewed, open access, scholarly journal, created in response to the rising incidence of chronic respiratory diseases worldwide. It publishes high quality research papers and original articles that have immediate relevance to clinical practice and its multi-disciplinary perspective reflects the nature of modern treatment. The journal provides a high quality, multi-disciplinary focus for the publication of original papers, reviews and commentary in the broad area of chronic respiratory disease, particularly its treatment and management.
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