COVID-19患者的住院时间和重症监护室停留时间与体重指数有关,会影响心肺功能。

IF 3.5 3区 医学 Q2 RESPIRATORY SYSTEM
Eulogio Pleguezuelos, Amin Del Carmen, Mateu Serra, Eva Moreno, Marc Miravitlles, Manuel Vicente Garnacho-Castaño
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引用次数: 0

摘要

背景:2019年冠状病毒病(COVID-19)对住院肥胖患者心肺功能的影响至关重要。本研究旨在分析住院和重症监护室(ICU)的时间以及体重指数如何影响 COVID-19 患者的心肺功能。方法:将 251 名参与者(男性,n = 118;女性,n = 133)分为四组:未住院的 COVID-19 患者(n = 65,年龄:45.3岁)、住院的COVID-19患者(n = 63,年龄:57.6岁)、入住重症监护室的COVID-19患者(n = 61,年龄:56.9岁)和对照组(n = 62,年龄:49.8岁)。在出院后 3 到 6 周之间进行了增量心肺运动测试:结果:体重正常(NW)的 ICU 患者的峰值摄氧量(VO2peak)、通气效率和动力输出均高于超重(OW)(平均差异:分别为 0.1 L-min-1、-5.5、29.0 W)和肥胖(OB)的 ICU 患者(平均差异:分别为 0.1 L-min-1、-5.0、26.2 W)(P < .05)。在 NW、OW 和 OB 参与者中,观察到对照组的 VO2 峰值和功率输出高于非住院组(平均差异:NW:0.2 L-min-1,OW:0.2 L-min-1,OB:0.2 L-min-1):NW:0.2 L-min-1,83.3 W;OW:0.2 L-min-1,60.0 W;OB:0.2 L-min-1,60.0 W):分别为 0.2 L-min-1、70.9 W)、住院组(平均差异:NW:0.2 L-min-1、83.3 W;OW:0.2 L-min-1、60.0 W;OB:0.2 L-min-1、70.9 WNW:0.2 L-min-1,72.9 W;OW:0.1 L-min-1,58.3 W;OB:0.2 L-min-1,70.9 W):分别为 0.2 升-分钟-1,91.1 瓦)和重症监护室患者(平均差异:NW:0.1 升-分钟-1,72.9 瓦;OW:0.1 升-分钟-1,58.3 瓦;OB:0.2 升-分钟-1,91.1 瓦):NW:0.1 L-min-1,70.9 W;OW:0.2 L-min-1,91.1 W;OB:结论:结论:COVID-19 的严重程度,尤其是住院和入住重症监护室的情况,以及肥胖和超重是降低 COVID-19 患者心肺功能的关键因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Hospital and intensive care unit stay associated with body mass index affect cardiorespiratory fitness in patients with COVID-19.

Background: The effects of coronavirus disease 2019 (COVID-19) on the cardiorespiratory fitness of hospitalized and obese patients are of utmost relevance. This study aimed to analyze how hospital and intensive care unit (ICU) stay together with body mass index affect cardiorespiratory fitness in patients with COVID-19.

Methods: 251 participants (males, n = 118; females, n = 133) were assigned to four groups: non-hospitalized COVID-19 patients (n = 65, age: 45.3 years), hospitalized COVID-19 patients (n = 63, age: 57.6 years), COVID-19 patients admitted to the ICU (n = 61, age: 56.9 years), and control group (n = 62, age: 49.8 years). An incremental cardiopulmonary exercise test was performed between 3 and 6 weeks after medical discharge from hospital.

Results: Higher peak oxygen uptake (VO2peak), ventilatory efficiency and power output were found in ICU patients with normal weight (NW) than in overweight (OW) (Mean difference: 0.1 L·min-1, -5.5, 29.0 W, respectively) and obese (OB) ICU patients (Mean difference: 0.1 L·min-1, -5.0, 26.2 W, respectively) (p < .05). In NW, OW and OB participants, higher VO2peak and power output were observed in control group compared with non-hospitalized (Mean difference: NW: 0.2 L·min-1, 83.3 W; OW: 0.2 L·min-1, 60.0 W; OB: 0.2 L·min-1, 70.9 W, respectively), hospitalized (Mean difference: NW: 0.2 L·min-1, 72.9 W; OW: 0.1 L·min-1, 58.3 W; OB: 0.2 L•min-1, 91.1 W, respectively) and ICU patients (Mean difference: NW: 0.1 L·min-1, 70.9 W; OW: 0.2 L·min-1, 91.1 W; OB: 0.3 L·min-1; 65.0 W, respectively) (p < .05).

Conclusions: The degree of severity of COVID-19, especially identified by hospitalization and ICU stay, together with obesity and overweight were key factors in reducing cardiorespiratory fitness in patients with COVID-19.

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来源期刊
Chronic Respiratory Disease
Chronic Respiratory Disease RESPIRATORY SYSTEM-
CiteScore
5.90
自引率
7.30%
发文量
47
审稿时长
11 weeks
期刊介绍: Chronic Respiratory Disease is a peer-reviewed, open access, scholarly journal, created in response to the rising incidence of chronic respiratory diseases worldwide. It publishes high quality research papers and original articles that have immediate relevance to clinical practice and its multi-disciplinary perspective reflects the nature of modern treatment. The journal provides a high quality, multi-disciplinary focus for the publication of original papers, reviews and commentary in the broad area of chronic respiratory disease, particularly its treatment and management.
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