Atroposelective N–N Axes Synthesis via Electrochemical Cobalt Catalysis

Here, we disclosed an unprecedented cobalt electrocatalyzed atroposelective C–H activation and annulation for the efficient construction of diversely functionalized N–N axes in an undivided cell. A broad range of allene substrates and benzamides bearing different functionalities are compatible with generating axially chiral products with good yields and excellent enantioselectivities (up to 92% yield and 99% ee). A series of synthetic applications and control experiments were also performed, which further expanded the practicality of this strategy.